Electrical stimulation of the brain (ESB) of unanesthetized animals offers a powerful technique for the study of brain structure and function. The method was originally employed by physiologists interested in determining the functional organization of the nervous system (Hess, 1957; Ranson 5 Magoun, 1939). But recently, psychologists have utilized stimulation with the object of determining the role of the central nervous system in the control of behavior. [...]

The electroencephalogram (EEG) has made a limited contribution to an understanding of psychological processes. Changes in the frequency and localization of the predominant background rhythms parallel physiological development from infancy to adulthood; variations of the normal EEG pattern also reflect changes in the states of sleep and waking. [...]

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A new method for the estimation of the EEG evoked potential (EP) is presented in this thesis. This method is based on a new model of the EEG response which is assumed to be the sum of the EP and independent correlated Gaussian noise representing the spontaneous EEG activity. The EP is assumed to vary in both shape and latency, with the shape variation represented by correlated Gaussian noise which is modulated by the EP. The latency of the EP is also assumed to vary over the ensemble of responses in a random manner governed by some unspecified probability density. No assumption on stationarity is needed for the noise. / With the model described in state-space form, a Kalman filter is constructed, and the variance of the innovation process of the response measurements is derived. A maximum likelihood solution to the EP estimation problem is then obtained via this innovation process. / Tests using simulated responses show that the method is effective in estimating the EP signal at signal-to-noise ratio as low as -6db. Other tests using real normal visual response data yield reasonably consistent EP estimates whose main components are narrower and larger than the ensemble average. In addition, the likelihood function obtained by our method can be used as a discriminant between normal and abnormal responses, and it requires smaller ensembles than other methods.

Thesis (Masters by Research) - Swinburne University of Technology, Brain Sciences Institute, 1999. / "A thesis submitted of the requirement for the award of the degree Masters by Research, Brain Sciences Institute - 1999. Typescript. Includes bibliographical references (p. 141-164).

Thesis (M.S.)--Rochester Institute of Technology, 2007. / Typescript. Includes bibliographical references (leaves 89-92).

Thèse--Paris. / At head of title: Université de Paris. Faculté des lettres et sciences humaines. Includes bibliographical references.

Thesis (Ph. D.)--University of Oregon, 2007. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 126-133). Also available for download via the World Wide Web; free to University of Oregon users.

Thesis (Ph. D.)--University of North Texas, Aug., 2008. / Title from title page display. Includes bibliographical references.