Epilepsy affects up to 1% of the world's population and approximately 2.5 million people in the United States. A considerable portion (30%) of epilepsy patients are refractory to antiepileptic drugs (AEDs), and surgery can not be an effective candidate if the focus of the seizure is on the eloquent cortex. To overcome the problems with existing solutions, a notable portion of biomedical research is focused on developing an implantable or wearable system for automated seizure detection and control. Seizure detection algorithms based on signal rejection algorithms (SRA), deep neural networks (DNN), and neighborhood component analysis (NCA) have been proposed in the IoMT framework. The algorithms proposed in this work have been validated with both scalp and intracranial electroencephalography (EEG, icEEG), and demonstrate high classification accuracy, sensitivity, and specificity. The occurrence of seizure can be controlled by direct drug injection into the epileptogenic zone, which enhances the efficacy of the AEDs. Piezoelectric and electromagnetic micropumps have been explored for the use of a drug delivery unit, as they provide accurate drug flow and reduce power consumption. The reduction in power consumption as a result of minimal circuitry employed by the drug delivery system is making it suitable for practical biomedical applications. The IoMT inclusion enables remote health activity monitoring, remote data sharing, and access, which advances the current healthcare modality for epilepsy considerably.

Ubiquitous computing is already weaving itself around us and it is connecting everything to the network of networks. This interconnection of objects to the internet is new computing paradigm called the Internet of Things (IoT) networks. Many capacity and non-capacity constrained devices, such as sensors are connecting to the Internet. These devices interact with each other through the network and provide a new experience to its users. In order to make full use of this ubiquitous paradigm, security on IoT is important. There are problems with privacy concerns regarding certain algorithms that are on IoT, particularly in the area that relates to their avalanche effect means that a small change in the plaintext or key should create a significant change in the ciphertext. The higher the significant change, the higher the security if that algorithm. If the avalanche effect of an algorithm is less than 50% then that algorithm is weak and can create security undesirability in any network. In this, case IoT. In this study, we propose to do the following: (1) Search and select existing block cryptographic algorithms (maximum of ten) used for authentication and encryption from different devices used on IoT. (2) Analyse the avalanche effect of select cryptographic algorithms and determine if they give efficient authentication on IoT. (3) Improve their avalanche effect by designing a mathematical model that improves their robustness against attacks. This is done through the usage of the initial vector XORed with plaintext and final vector XORed with cipher tect. (4) Test the new mathematical model for any enhancement on the avalanche effect of each algorithm as stated in the preceding sentences. (5) Propose future work on how to enhance security on IoT. Results show that when using the proposed method with variation of key, the avalanche effect significantly improved for seven out of ten algorithms. This means that we have managed to improve 70% of algorithms tested. Therefore indicating a substantial success rate for the proposed method as far as the avalanche effect is concerned. We propose that the seven algorithms be replaced by our improved versions in each of their implementation on IoT whenever the plaintext is varied. / Electrical and Mining Engineering / M. Tech. (Electrical Engineering)