M.Tech. / The study was aimed at determining the efficacy of the homoeopathic simillimum in the treatment of endometriosis. Endometriosis may be defined as the presence of endometrial tissue outside the uterine cavity and is often associated with severe pain and infertility. The homoeopathic simillimum is the single remedy prescribed that most closely matches the symptoms presented by the participant. Symptoms from the physical, mental and emotional plane are taken into account when prescribing the simillimum remedy. The ten participants taking part in the study were evaluated at monthly intervals over a period of four months. The participants were assessed on different levels including mental, physical and emotional and the homoeopathic remedies were individually prescribed for each participant. Participants were required to record all symptoms experienced on a daily basis and report back at the monthly evaluation. The results of the daily evaluation and the observations, made by the researcher at each monthly visit, enabled the researcher to determine the efficacy of the homoeopathic treatment. The results of the daily evaluations were statistically analysed using the Analysis of Variance technique and the Chi-squared statistic to test for associations. The study showed a statistically significant improvement in the amount of bleeding, constipation, depression, diarrhoea, nausea and pelvic pain experienced by the participants and a not statistically significant improvement was shown for well-being, vomiting, dysmenorrhoea and dyspareunia. The women taking part in the study felt there was an improvement in the majority of symptoms associated with endometriosis. Therefore, the homoeopathic simillimum has proved benefit

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