The goal of this work is to modify an existing course module on engineering better medicines to produce a more engaging physiologically realistic and pedagogically sound curriculum. The original module explored drug delivery using a one-compartment model, which examined only the dissolution of medicine; the module relied on a traditional teacher lead pedagogy. The curriculum modifications include engineering a two-compartment model students use to test the medicines they design, incorporating both dissolution and transfer to the blood and project based learning strategies have been added to produce a student centered project. The purpose of these modifications is to produce a curriculum successful in providing a diverse group of students, both male and female, of all socioeconomic backgrounds as well as ethnic and cultural groups with a positive engineering experience. / text