Nanoscale materials usually present strikingly different properties in comparison with their bulk counterparts, such as quantum size effects, surface plasmon resonance (SPR). To explore new properties as well as for novel applications, nanomaterials are being extensively investigated. This project investigates the interactions of electromagnetic fields with nanoscale materials, particularly gold nanoparticles (GNPs), over a wide range of frequency bands, including static field, 261 kHz, 13.56 MHz, 2.45 GHz, millimetre wave, THz, and the visible light. Especially, the efforts have been devoted to the study of heating effect of GNPs in association with potential biomedical applications. To explain the electromagnetic heating of GNPs, dielectric properties of GNP dispersions has been studied from 100 MHz to 20 GHz, as well as in the millimetre wave and THz ranges. The static field induced effects on the size distribution of GNPs has also been examined using ultra-violet spectroscopy and correlated to SPR. It has been revealed that purified GNPs cannot increase the specific absorption rate substantially at whichever frequency points of 261 kHz, 13.56 MHz, or 2.45 GHz. However, a greater temperature rise has been observed in the impurified GNP dispersions compared to deionisedwater, after 10 min RF treatment at 13.56 MHz. The measurements on dielectric properties show that impurified samples have much higher effective conductivity than that of deionised-water, while the conductivity change of purified ones is very small and not detectable within the measurement accuracy. This observation supports that the heating effect of GNP dispersions is mostly contributed by the impurities and disproves that GNPs can increase the specific absorption rate significantly. The magnetic field heating at 261 kHz suggests that GNPs have very weak magnetic properties. It has been found that a static field can change the size distribution of GNPs. Up to 2 THz, it is measured that the dielectric properties of GNP dispersions have no convincing change compared to deionised-water, implying that the electromagnetic heating of GNP below 2 THz may be insignificant. In addition, it is confirmed that GNPs have strong absorption in the visible light range due to SPR.

Les nanomatériaux manufacturés (comme les nanoparticules d’oxydes métalliques, les nanotubes de carbone, les nanofibres etc.) possèdent des propriétés remarquables qui leur confèrent des applications industrielles innovantes. Néanmoins, ces nouveaux matériaux soulèvent des inquiétudes vis à vis de leurs potentiels risques. Ces nanomatériaux manufacturés connaissent une production et une commercialisation croissantes. Par conséquent, de plus en plus de personnes sont potentiellement exposées à ces nanomatériaux (aussi bien les consommateurs que les opérateurs) à travers les aérosols qui pourraient être émis au cours du cycle de vie du matériau. L’une des approches possibles de réduction de risque serait la prévention de l’émission qui consisterait en une conception réfléchie du matériau avec un compromis performance/sûreté. La thèse présentée ici suit cette approche. Il s’agit de comprendre le phénomène et les mécanismes d’émission des nanomatériaux manufacturés à l’aide d’outils théoriques et expérimentaux. Le dispositif expérimental développé au cours de cette étude vise (i) à reproduire à l’échelle laboratoire des activités en conditions réelles, (ii) à identifier les mécanismes d’émission, et (iii) à mener simultanément des analyses qualitatives et quantitatives* des nanomatériaux manufacturés émis. Pour la sollicitation mécanique, le procédé d’abrasion a été choisi ; quant au vieillissement environnemental, le choix s’est porté sur un procédé d’exposition accélérée aux rayons d’UV en présence d’humidité et de chaleur. Les résultats suggèrent que les entités microscopiques présentes à la surface d’un matériau (appelées aspérités ou rugosités) subissent globalement 4 types de mécanismes d’enlèvement pendant l’abrasion, suivant la variation de 18 paramètres (liés au matériau et au procédé). Ces mécanismes déterminent la forme, la taille et le nombre de particules de l’aérosol émis. De plus, dans le cas des échantillons testés dans les conditions expérimentales données, il a été observé, lors des essais mécaniques seuls, la génération d’aérosols dans lesquels sont retrouvées des nanomatériaux manufacturés liées à leur matrice. Il s’agit de particules nanométriques et micrométriques. Cependant, dans le cas du couplage abrasion/vieillissement environnemental, après un temps donné de détérioration, il est constaté l’émission de nanomatériaux manufacturés libres, en plus des nanomatériaux manufacturés liés à leur matrice. Les résultats expérimentaux relatifs aux sollicitations mécaniques ont été mis en corrélation avec des lois de mécanique classique utilisant des modèles analytiques. Le modèle utilise en partie des relations semi-empiriques ; après ajustement, on observe une très bonne convergence modèle-expérience. Ce modèle a été utilisé pour réaliser une étude de sensibilité sur les 18 paramètres évoqués précédemment, et ce pour une variation de 25% pour chaque paramètre. Ceci permet d'illustrer la capacité du modèle à hiérarchiser l'influence des différents paramètres sur l'émission de particules, pour des conditions données. Ainsi, ce travail a permis de développer un ensemble constitué d’une part d’outils expérimentaux et d’autre part d’un modèle. Si cet ensemble est largement perfectible, il permet toutefois d’ores et déjà d’entamer une conception “nanosafe by design”. / Engineering nanomaterials (ENM) like metal oxide nanoparticles, carbon nanotubes, nanofibers, etc. possess various innovative properties and their industrial use creates new opportunities. However, they also present new risks and uncertainties. There is an ever growing production and use of the products containing these ENM, like nanocomposites or nanocoatings, which result in an increasing number of workers and consumers exposed to ENM upon their emission (in the form of aerosols) from the products containing them. One of the most favored approaches, to minimize this emission, would be a preventive one which would focus on altering the product’s material properties during its design phase itself without compromising with any of its added benefits.This thesis advocates this approach. It attempts to understand the ENM emission phenomenon and its yielding mechanisms on the basis of combined experimental and theoretical approaches. The experimental set-up, developed during this thesis, is equipped with the necessary elements which can (i) seek to reproduce the real life activities on a laboratory scale (ii) identify the emission mechanism (iii) carry out both qualitative as well as quantitative*analysis of the emitted ENM simultaneously. Whilst the mean chosen for applying the mechanical solicitation or stress is an abrasion process, for the environmental weathering, it is an accelerated UV exposure process in the presence of humidity and heat. The results suggest that depending upon 18 material and process properties/parameters, the microscopic entities present on the surface of a product, called asperities, undergo mainly 4 types of removal mechanisms during abrasion. It is these mechanisms that decide the shape, size and the number of the aerosol particles emitted. Moreover, for the given test samples and experimental conditions studied during the thesis, application of the mechanical stresses alone was found to generate the emitted ENM aerosols in which ENM is always embedded inside the product matrix, thus, a representative product element. In such a case, the emitted aerosols comprise of both nanoparticles as well as microparticles. But if the mechanical stresses are coupled with the environmental weathering, then the eventual deterioration of the product, after a certain weathering duration, may lead to the emission of the free ENM aerosols too. All these experimental findings, pertaining to the effect of the mechanical stresses alone, have also been put into the perspective with classical material and mechanics state laws using a predictive analytical model. A close agreement** of the estimated results of this model with the experimentally measured ones has validated its functioning. This model was used to perform a sensitivity analysis on the aforementioned 18 parameters to rank the influence of a25% variation in each of their values on the particle emission for the given conditions.Thus, during the present thesis, both experimental and theoretical approaches have been developed to study the emission. Despite the fact that these approaches are perfectible, they can still be used during product design phase for the product to be “nanosafe by design”.