Serum lactic dehydrogenase, serum glutamic oxaloacetic transaminase, and lactic dehydrogenase isoenzyme (LDH5) levels were studied on fifteen Ball State University athletes who sustained contusions, hematomas, and muscle strains.Each individual's injury was classified as mild, moderate, or severe. There were seven subjects sustaining injuries classified as mild, seven receiving moderate injuries, and one individual with a severe injury.Serum enzyme levels of all subjects were elevated above controls after injury and then proceeded to decline unless re-injury occurred.The enzyme levels for the moderate group, as demonstrated by the graphs, revealed more marked elevations for LDH and GOT than did the ones in the mild group.A significant statistical difference was found to exist between the mild and moderate groups involving the total LDH. There were no statistical differences between these groups Sand the GOT or LDH5 isoenzyme levels.

Thesis (MTech. degree in Pharmaceutical Sciences)--Tshwane University of Technology, 2008. / The aim of the study is to investigate whether the chemical composition and antimicrobial activity of orally administered medicinal plants are affected by in vitro dissolution and gastrointestinal absorption processes. Few in vitro screening assays for biological activities of plant extracts consider the effect of the gastrointestinal system. This is an important factor for the bioavailability of plant extracts intended to be administered via the oral route. In this study, crude water and methanol extracts of selected plants (green tea, 'buchu', thyme, sage and wild camphor) were prepared and exposed to simulated gastric fluid and simulated intestinal fluid during dissolution studies. The crude extracts and resulting simulated gastric fluid and simulated intestinal fluid products were screened for antimicrobial activity.