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1	Twin and Family Risk from Environment and Epigenetics (FREE) Studies Reveal Strong Environmental and Weaker Genetic Cues That Explain High Heritability of Eosinophilic Esophagitis Alexander, Eileen Steinle, M.S. 02 September 2014 (has links) No description available. Environmental Health eosinophilia medical genetics twin and family-based environment gastrointestinal diseases epigenetic methylation
2	Vznik, přenos a ekologický význam apomixie v rodě Hieracium s.str.: role genetických a epigenetických mechanismů. / Origin, inheritance and ecological sygnificance of apomixis in the genus Hieracium s.str.: the role of genetic and epigenetic mechanims Pinc, Jan January 2020 (has links) Apomixis (asexual reproduction by seeds) has the considerable potential in agriculture and crop breeding due to its ability to produce genetically identical progenies in a form of persistent propagules, i.e. seeds. However, the processes laying behind the origin of apomixis and connected molecular mechanisms are still unknown. Despite the fact, that apomicts are considered to be an evolutionary dead-ends, they are often more widely distributed than their sexual relatives (this phenomenon is commonly referred to as geographical parthenogenesis (GP). Although this phenomenon is studied for decades, its causes are still not fully understood. Importantly, several recent studies pointed out that apomicts with limited genetic variability can at some extent react to changing environment through changes in gene transcription by epigenetic modifications. It is generally assumed, that hybridisation and polyploidization played a crucial role in the emergence of apomixis. For this reason, presented studies test the putative origin of selected polyploid apomicts and if the interspecific hybridisation between diploid sexuals triggers polyploidization using predominantly polyploid and apomictic genus Hieracium s. str. Surprisingly, the presented study demonstrates the hybrid origin of almost all investigated...
3	Etablierung eines Verfahrens zum Nachweis epigenetischer Biomarker im peripheren Blut zur Stratifizierung der Therapie des Rektumkarzinoms / Fully-automated hypermethylation testing by One-Step-Real-Time-PCR of 6 different potential epigenetic biomarkers in peripheral blood for rectal cancer detection and follow-up. Thormann, Tobias 17 December 2015 (has links) No description available. 610 Ein-Schritt-Real-Time-PCR Epigenetische Biomarker Therapiestratifizierung Rektumkarzinom Restriktionsendonuklease Bisulfit-Konversion Rectal Cancer RUNX3 NEUROG1 HLTF SEPTIN9 TMEFF2 SDC2 RASSF1A CpG-Island-Methylation One-Step-Real-Time-PCR Epigenetic Methylation Hypermethylation

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Twin and Family Risk from Environment and Epigenetics (FREE) Studies Reveal Strong Environmental and Weaker Genetic Cues That Explain High Heritability of Eosinophilic Esophagitis

Vznik, přenos a ekologický význam apomixie v rodě Hieracium s.str.: role genetických a epigenetických mechanismů. / Origin, inheritance and ecological sygnificance of apomixis in the genus Hieracium s.str.: the role of genetic and epigenetic mechanims