In Shannon’s seminal paper, “A Mathematical Theory of Communication”, he defined ”Channel Capacity” which predicted the ultimate performance that transmission systems can achieve and suggested that capacity is achievable by error-correcting (channel) coding. The main idea of error-correcting codes is to add redundancy to the information to be transmitted so that the receiver can explore the correlation between transmitted information and redundancy and correct or detect errors caused by channels afterward. The discovery of turbo codes and rediscovery of Low Density Parity Check codes (LDPC) have revived the research in channel coding with novel ideas and techniques on code concatenation, iterative decoding, graph-based construction and design based on density evolution. This dissertation focuses on the design aspect of graph-based channel codes such as LDPC and Irregular Repeat Accumulate (IRA) codes via density evolution, and use the technique (density evolution) to design IRA codes for scalable image/video communication and LDPC codes for distributed source coding, which can be considered as a channel coding problem. The first part of the dissertation includes design and analysis of rate-compatible IRA codes for scalable image transmission systems. This part presents the analysis with density evolution the effect of puncturing applied to IRA codes and the asymptotic analysis of the performance of the systems. In the second part of the dissertation, we consider designing source-optimized IRA codes. The idea is to take advantage of the capability of Unequal Error Protection (UEP) of IRA codes against errors because of their irregularities. In video and image transmission systems, the performance is measured by Peak Signal to Noise Ratio (PSNR). We propose an approach to design IRA codes optimized for such a criterion. In the third part of the dissertation, we investigate Slepian-Wolf coding problem using LDPC codes. The problems to be addressed include coding problem involving multiple sources and non-binary sources, and coding using multi-level codes and nonbinary codes.