Thesis (M.Sc.)--University of Alberta, 2009. / A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science, Department of Psychiatry. Title from pdf file main screen (viewed on October 31, 2009). Includes bibliographical references.

Thesis (Ph. D.)--University of Texas at Austin, 2006. / Vita. Includes bibliographical references and index.

Thesis (Ph. D.)--Duke University, 2007. / Includes bibliographical references.

Akademisk avhandling - Karolinska institutet, Stockholm. / Added title page, with thesis note, inserted. Bibliography: p. [97]-101.

Thesis (doctoral)--Rijksuniversiteit te Groningen, 1980. / Summary and vita in Dutch. Highlights sheet in Dutch inserted. Vita. Includes bibliographical references (p. 125-140).

Thesis (Ph. D.)--University of Florida, 1982. / Description based on print version record. Typescript. Vita. Includes bibliographical references (leaves 72-74).

No description available.

No description available.

abstract: Following a traumatic brain injury (TBI) 5-50% of patients will develop post traumatic epilepsy (PTE). Pediatric patients are most susceptible with the highest incidence of PTE. Currently, we cannot prevent the development of PTE and knowledge of basic mechanisms are unknown. This has led to several shortcomings to the treatment of PTE, one of which is the use of anticonvulsant medication to the population of TBI patients that are not likely to develop PTE. The complication of identifying the two populations has been hindered by the ability to find a marker to the pathogenesis of PTE. The central hypothesis of this dissertation is that following TBI, the cortex undergoes distinct cellular and synaptic reorganization that facilitates cortical excitability and promotes seizure development. Chapter 2 of this dissertation details excitatory and inhibitory changes in the rat cortex after severe TBI. This dissertation aims to identify cortical changes to a single cell level after severe TBI using whole cell patch clamp and electroencephalogram electrophysiology. The work of this dissertation concluded that excitatory and inhibitory synaptic activity in cortical controlled impact (CCI) animals showed the development of distinct burst discharges that were not present in control animals. The results suggest that CCI induces early "silent" seizures that are detectable on EEG and correlate with changes to the synaptic excitability in the cortex. The synaptic changes and development of burst discharges may play an important role in synchronizing the network and promoting the development of PTE. / Dissertation/Thesis / Masters Thesis Biology 2014

[pt] Os sistemas de potência são projetados para operarem com tensão e freqüência constantes, admitindo-se pequenas variações em torno de sues valores nominais. Estas grandezas são controladas principalmente pelos sistemas de excitação e reguladores de velocidade, respectivamente. Esta dissertação examina o projeto de sistemas de excitação modernos e estabelece as características de projeto dos componentes das excitatrizes estáticas. Os principais componentes (conversor, circuito de disparo, circuito de partida e regulador de tensão) são implementados em um protótipo de excitatriz. As respostas do protótipo à pequenas e grandes perturbações também são discutidas. / [en] Power systems are designed to operate with constant voltagem and frequency, allowing small sinal variations around its rated valves. These quantities are mainly controlled by excitation systems and governors, respectively. This dissertation examines the design of modern excitation systems and estabilishes the desired characteristics of static exciter componentes. The main components (conversor, firing circuit, starting circuit and voltage regulator) are implemented in a exciter prototype. The prototype response to small and larger disturbances are also discussed.