This dissertation addresses the modeling and solution of mixed-integer linear multistage stochastic programming problems involving both endogenous and exogenous uncertain parameters. We propose a composite scenario tree that captures both types of uncertainty, and we exploit its unique structure to derive new theoretical properties that can drastically reduce the number of non-anticipativity constraints (NACs). Since the reduced model is often still intractable, we discuss two special solution approaches. The first is a sequential scenario decomposition heuristic in which we sequentially solve endogenous MILP subproblems to determine the binary investment decisions, fix these decisions to satisfy the first-period and exogenous NACs, and then solve the resulting model to obtain a feasible solution. The second approach is Lagrangean decomposition. We present numerical results for a process network planning problem and an oilfield development planning problem. The results clearly demonstrate the efficiency of the special solution methods over solving the reduced model directly. To further generalize this work, we also propose a graph-theory algorithm for non-anticipativity constraint reduction in problems with arbitrary scenario sets. Finally, in a break from the rest of the thesis, we present the basics of stochastic programming for non-expert users.