Flexible printed circuits (FPCs) have a flexible character, so the topic for high accuracy and speed of drill is important. We will create an automatic system that joins vision-guided function to accomplish the challenge object of high quality and low cost. The system must contain two sub-systems, which are the machine position control and the image recognition. The machine position control system basis framework moves to position after getting hole-position with different methods and scheme of trajectory planning. The image recognition system framework exports correction to machine position control system that integrates the technique of charge-coupled device (CCD), light source design, snap an image in region of interest (ROI) with image grabber card, pattern match that uses normalized cross correlation (NCC) algorithm. We can proof that the system can achieve the expected goal of high speed and accuracy of drill.