Abstract Much warranted attention over the past few decades has been devoted to the problem of retaining women faculty in academe, particularly in areas where they poorly represented such as in science, technology, engineering, and mathematics (STEM) fields. This study uses descriptive statistics and structural equation modeling techniques to test an existing model of general faculty departure intentions (Zhou & Volkwein, 2004) on three samples of faculty (a) women faculty, (b) women faculty in STEM, and (c) women faculty in non-STEM fields. Findings revealed that although several significant pathways to intention to leave for women faculty in STEM and in non-STEM fields were identified, the tested model is not an overall good fit of the data for any of the three samples, implying the need for new models of faculty departure intentions specifically for women in STEM and non-STEM disciplines. Implications for practice, theory, and future research are discussed.