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The effects of human serum albumin mutations on physiologically important fatty acid transportTuei, Vivian C January 2007 (has links)
Thesis (M.S.)--University of Hawaii at Manoa, 2007. / Includes bibliographical references (leaves 46-54). / x, 54 leaves, bound ill. 29 cm
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Protein-bound fatty acids in mammalian hair fibres /Peet, Daniel J. January 1994 (has links)
Thesis (Ph. D.)--University of Melbourne, 1995. / Typescript (photocopy). Addendum inserted. Includes bibliographical references (leaves 155-179).
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A superior early myocardial infarction marker : human heart-type fatty acid-binding protein /Chan, Cangel Pui Yee. January 2002 (has links)
Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2002. / Includes bibliographical references (leaves 139-166). Also available in electronic version. Access restricted to campus users.
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Identification of plant-parasitic nematodes using FAME analysisSekora, Nicholas Scott. Lawrence, Katheryn Kay Scott, January 2009 (has links)
Thesis--Auburn University, 2009. / Abstract. Includes bibliographical references.
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Adipocyte fatty acid-binding protein a link between inflammation and vascular dysfunction /Li, Huiying, January 2010 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 92-107). Also available in print.
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Adipocyte fatty acid-binding protein : a link between inflammation and vascular dysfunction /Li, Huiying, January 2010 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 92-107). Also available online.
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Adipocyte- and epidermal-fatty acid-binding proteins in relation to obesity and its medical complicationsYeung, Chun-yu, January 2009 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 203-231). Also available in print.
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Characterization of mitochondrial 2-enoyl thioester reductase involved in respiratory competenceTorkko, J. (Juha) 23 May 2003 (has links)
Abstract
Maintenance of the mitochondrial respiratory chain complexes plays crucial role for the aerobic metabolism of the eukaryotes such as unicellular yeasts, for example, Saccharomyces cerevisiae as well as of human being.
Mitochondrial respiratory function has been studied using the yeast S. cerevisiae as a model organism. Since yeast cells are also able to grow without respiration by fermentation, identification of the nuclear genes linked to respiratory function is possible by generation of nuclear gene deletions and testing for respiration-deficient phenotype of the yeast deletion strains id est for yeast cells only poorly or not at all growing on the media containing non-fermentable carbon sources.
This study reports identification of a novel mitochondrial 2-enoyl thioester reductase from the yeasts Candida tropicalis and S. cerevisiae, Etr1p and Mrf1p, respectively. Examination of the function of these proteins in the respiration-deficient mrf1Δ strain from S. cerevisiae suggests that the reductase is involved in mitochondrial fatty acid synthesis (FAS type II) in the yeast. Site-directed mutagenesis of a conserved tyrosine in the catalytic site of the enzyme indicated that the 2-enoyl thioester reductase activity is critical for mitochondrial respiratory competence. In addition, subcellular localization to mitochondria was required for the complementation of the respiration-deficient phenotype of the yeast reductase deletion strain. The crystal structure for the Etr catalytic site mutant indicated the structural integrity of the mutant supporting the requirement of the tyrosine for the catalysis.
Characterization of Etr crystal structures both in apo- and holo-forms containing NADPH established Etr as a member of novel subfamily of enoyl thioester reductases in the superfamily of medium-chain dehydrogenases/reductases (MDR). Two isoforms of Etr with the difference in three amino acids only are encoded by two distinct genes in C. tropicalis, whereas only single gene encodes the reductase functioning in the mitochondria in S. cerevisiae. The presence of two genes in C. tropicalis was taken as an example of genetic redundancy in this yeast, the two genes also shown to be expressed in slightly different ways under various carbon sources available for growth.
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Tissue enzymes concerned with the metabolism and transport of fatsSalaman, M. R. January 1964 (has links)
No description available.
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Mosquito Larvicides from CyanobacteriaBerry, Gerald A 16 April 2014 (has links)
Cyanobacteria (blue-green algae) produce a diverse array of toxic or otherwise bioactive metabolites. These allelochemicals may also play a role in defense against potential predators and grazers, particularly aquatic invertebrates and their larvae, including mosquitoes. Compounds derived from cyanobacteria collected from the Florida Everglades and other Florida waterways were investigated as insecticides against the mosquito Aedes aegypti, a vector of dengue and yellow fever. Screening of cyanobacterial biomass revealed several strains that exhibited mosquito larvicidal activity. Guided via bioassay guided fractionation, a non-polar compound from Leptolyngbya sp. 21-9-3 was found to be the most active component. Characterization revealed the prospective compound to be a monounsaturated fatty acid with the molecular formula C16H30O2. This is the first evidence of mosquito larvicidal activity for this particular fatty acid. With larvicidal becoming more prevalent, fatty acids should be explored for future mosquito control strategies.
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