During neural activity, action potentials travel down axons, generating effective charge current pulses, which are central in neuron-to-neuron communication. Consequently, said current pulses generate associated magnetic fields with amplitudes on the order of picotesla (pT) and femtotesla (fT) and durations of 10’s of ms. Magnetoencephalography (MEG) is a technique used to measure the cortical magnetic fields associated with neural activity. MEG limitations include the inability to detect signals from deeper regions of the brain, the need to house the equipment in special magnetically shielded rooms to cancel out environmental noise, and the use of superconducting magnets, requiring cryogenic temperatures, bringing opportunities for new magnetic sensors to overcome these limitations and to further advance neuroscience. An extraordinary magnetoresistance (EMR) tunable graphene magnetometer could potentially achieve this goal. Its advantages are linear response at room temperature (RT), sensitivity enhancement owing to combination of geometric and Hall effects, microscale size to place the sensor closer to the source or macroscale size for large source area, and noise and sensitivity tailoring. The magnetic sensitivity of EMR sensors is, among others, strongly dependent on the charge mobility of the sensing graphene layer. Mechanisms affecting the carrier mobility in graphene monolayers include interactions between the substrate and graphene, such as electron-phonon scattering, charge impurities, and surface roughness. The present work reviews and proposes a material set for increasing graphene mobility, thus providing a pathway towards pT and fT detection. The successful fabrication of large-size magnetic sensors employing CVD graphene is described, as well as the fabrication of trilayer magnetic sensors employing mechanical exfoliation of h-BN and graphene. The magneto-transport response of CVD graphene Hall bar and EMR magnetic sensors is compared to that obtained in equivalent trilayer devices. The sensor response characteristics are reported, and a determination is provided for key performance parameters such as current and voltage sensitivity and magnetic resolution. These parameters crucially depend on the material's intrinsic properties. The Hall cross magnetic sensor here reported has a magnetic sensitivity of ~ 600 nanotesla (nT). We find that the attained sensitivity of the devices here reported is limited by contaminants on the graphene surface, which negatively impact carrier mobility and carrier density, and by high contact resistance of ~2.7 kΩ µm at the metallic contacts. Reducing the contact resistance to < 150 Ω µm and eliminating surface contamination, as discussed in this work, paves the way towards pT and ultimately fT sensitivity using these novel magnetic sensors. Finite element modeling (FEM) is used to simulate the sensor response, which agrees with experimental data with an error of less than 3%. This enables the prediction and optimization of the magnetic sensor performance as a function of material parameters and fabrication changes. Predictive studies indicate that an EMR magnetic sensor could attain a sensitivity of 1.9 nT/√Hz employing graphene with carrier mobilities of 180,000 cm²/Vs, carrier densities of 1.3×10¹¹ cm^-2 and a device contact resistance of 150 Ω µm. This sensitivity increments to 443 pT/√Hz if the mobility is 245,000 cm²/Vs, carrier density is 1.6×10¹⁰ cm^-2, and a lower contact resistance of 30 Ω µm. Such devices could readily be deployed in wearable devices to detect biomagnetic signals originating from the human heart and skeletal muscles and for developing advanced human-machine interfaces.

<p>Composite Plate Shear Walls - Concrete Filled (C-PSW/CF), also known as SpeedCore walls, are increasingly used in commercial buildings. C-PSW/CF offer the advantages of modularization and expedited construction time. The performance of C-PSW/CF under wind and seismic loading has been extensively studied. As such, building codes permit the use of these walls in non-seismic and seismic regions. In addition to these lateral loads, C-PSW/CF may be exposed to fire loading during their service life. Elevated temperatures resulting from the fire loading subject structural components to a set of forces and deformations. These elevated temperatures result in the significant degradation of the material properties. Thus, fire loading may lead to the failure of structural components during fire incidents within the buildings.</p> <p>This dissertation describes (i) experimental, numerical, and analytical studies conducted to evaluate the performance of C-PSW/CF and (ii) the development of design guidelines for C-PSW/CF subjected to fire and gravity loading. The results from prior experimental investigations were compiled, and five additional fire tests were conducted to address gaps in the experimental data. The fire tests were conducted on laboratory-scale specimens subjected to axial compressive loading and simulated standard fire loading (heating). The parameters considered in the tests were axial compressive loading (21% – 30% of section compressive strength, <em>Ag f’c</em>), steel plate slenderness (24 – 48, tie spacing-to-steel plate thickness ratio), and uniformity of heating (all-sided versus three-sided heating).</p> <p>Numerical and analytical studies were conducted using two independent methods namely Finite Element (FE) and Finite Difference (FD) methods. The developed models were benchmarked to test data, and the benchmarked models were used to conduct parametric studies to expand the database. The thermal and structural material properties recommended by Eurocode standards were applied in these models. The parameters considered were the wall thickness (200 mm – 600 mm), wall slenderness (story height-to-concrete thickness ratio, <em>H/tc</em>= 5 – 25), axial load ratio (<em>Pu</em> ≤ 30% section concrete strength, <em>Ac f’c</em>), heating uniformity (uniform versus non-uniform heating), boundary conditions (pinned versus fixed), cross-sectional steel plate reinforcement ratio (<em>As/Ag</em> =1.3% – 5.3%), steel plate slenderness ratio (<em>stie/tp</em> = 20 – 75), tie bar spacing-to-wall concrete thickness ratio (<em>stie/tc</em> = 0.5 – 1.0), and concrete compressive strength (<em>f’c</em> = 40 MPa – 55 MPa).</p> <p>Symmetric nonlinear thermal gradients were developed through wall thickness for the walls exposed to uniform fire loading. Due to the low thermal conductivity of concrete, the temperature decreased nonlinearly through the wall thickness towards the mid-thickness of the walls. For the non-uniform fire exposure, temperatures through the wall thickness decreased nonlinearly towards the unexposed surface of the walls. A consistent trend was observed in the axial displacements of C-PSW/CF under combined fire and gravity loading. The observed trend consisted of several steps including (i) thermal expansion, (ii) gradual axial shortening, (iii) fast axial shortening, and (iv) failure.</p> <p>Local buckling of steel plates between tie bars was observed in all walls. However, this phenomenon did not cause any significant degradation in structural performance or failure of the walls. The results from parametric studies indicated that wall slenderness ratio (story height-to-wall thickness ratio), wall thickness, applied axial load ratio, and end boundary conditions have a significant influence on the fire resistance of C-PSW/CF. Higher wall slenderness ratios and load ratios had a detrimental effect on the fire resistance of walls. Global buckling was the dominant failure mode for the walls with high slenderness ratios (e.g., <em>H</em>/<em>tc </em>³ 15). In thicker walls, the lower temperatures in the middle regions of the concrete helped to maintain the axial compressive capacity of walls under fire loading. Limiting the steel plate slenderness ratio could slightly improve the fire resistance of unprotected walls by arresting the extent of local buckling between tie bars.</p> <p>The results from the parametric studies have been used to develop an approach for designing C-PSW/CF subjected to combined fire and gravity loading. The total (linear) length of the wall was discretized into unit width columns, where each unit width column corresponded to a length of wall equal to the tie bar spacing (<em>stie</em>). Thus, each unit is like a column with steel plates on two opposite surfaces, concrete infill, and tie bars distributed uniformly along the height. The axial load capacity of C-PSW/CF can be estimated as the axial load capacity of the unit width column, calculated using the developed approach, multiplied by the linear length of the wall divided by the unit width (tie bar spacing). For this approach, the wall slenderness ratio (<em>H/tw</em>), has a limiting value of 20. Walls with wall slenderness ratios greater than 20 should be fire protected. The expansion of the material on the exposed surface of walls generated moments through the wall cross-section in non-uniform fire scenarios. This phenomenon caused the early failure of walls (~40 minutes) with wall slenderness ratios greater than 20. An approach was developed to conservatively estimate the fire-resistance rating (in hours) of unprotected C-PSW/CF exposed to the standard fire time-temperature curve. The fire-resistance rating of C-PSW/CF depends directly on the applied axial load ratio, wall slenderness ratio, and wall thickness.</p> <p>The temperature profile through the wall thickness can be calculated by discretizing the section into fibers (or elements). Since the temperature of the elements is uniform along the height and length of walls, 1D thermal analysis (through wall thickness) can be performed using heat transfer equations or the fiber-based program developed in the study.</p> <p>Vent holes are recommended to relieve the buildup steam pressure as the moisture content of concrete evaporates at temperatures exceeding the boiling point of water. A rational method was developed to design the vent holes as a function of the maximum temperature and thermal gradient through the wall thickness, heating duration, moisture content, and the acceptable level of pressure buildup on the steel plates. However, in typical cases, unprotected C-PSW/CF walls can be provided with 25 mm diameter vent holes spaced at a distance equal to story height or 3.6 m (maximum) in the horizontal and vertical directions to relieve the buildup of steam or water vapor pressure.</p> <p>This research study also led to the development and validation of a computer program that can be used instead of the design equations to more accurately model and calculate the thermal and structural performance of composite C-PSW/CF. This program is based on a fiber-based section and member analysis method that can be used to evaluate the performance and axial (gravity) load capacity of unprotected and protected C-PSW/CF subjected to uniform or non-uniform heating. The analysis can be conducted by implementing standard (ISO 834 or ASTM E119), Eurocode parametric, or user input gas (or surface) time-temperature curves.</p> <p>The proposed equations and the recommendations in this study can be used to develop design guidelines and specifications for fire resistance design of C-PSW/CF under combined fire and gravity loading. A code change proposal will be proposed to AISC <em>Specification</em> - Appendix 4 (Structural Design for Fire Condition).</p>