Comprehensive emergency management and response is crucial for disaster prevention and health emergencies. However, in African countries with an abundance of natural disasters and a rising surge in cardiovascular and obstetric emergencies, little research exists on emergency response. This study examines the fire emergency response in Kumasi Metropolitan Assembly (KMA), Ghana's second largest city. We use Geographic Information Systems (GIS) tools including location -allocation modeling to evaluate the existing system of fire facilities, identify gaps in service, and suggest locations for new fire stations to maximize population coverage. Our results show that fire stations within KMA are poorly distributed and large portions of the metropolis are underserved, a situation that is partly responsible for the huge losses of lives and property during fire outbreaks.