This investigation explored the use of microcosms as a tool for studying the dynamics of tropical aquaculture ponds. The potential use of rabbit excreta as a pond fertilizer in integrated farming systems was also investigated. Twelve insulated fiber glass tanks were utilized as microcosms to simulate earthen ponds. Seven hand-sexed Nile Tilapia O. niloticus) were stocked per tank, and microcosm performance was observed for a 90- day experimental period. Three rabbit excreta loading rates corresponding to 50 and 75 kg/10,000 m³ /day, and a continuously adjusted manure loading rate were assessed. The fertilizer treatments were compared to a control treatment where fish were fed on a prepared food. Water quality variables and fish performance were regularly monitored. Nitrogen and phosphorous content of rabbit excreta were measured. The dynamics of the microcosms were similar to warm water earthen ponds with respect to physical and chemical characteristics. Statistical differences were detected between control and fertilized treatments in relation to dissolved oxygen levels, net primary productivity, total alkalinity, total ammonia and orthophosphate levels. Primary productivity was influenced more by light intensity and penetration than by nutrient limitation. Rabbit excreta overloading was observed in the 75 kg treatment. Fish growth was greatest in the control treatment, but it was not statistically different from the continuously adjusted fertilizer treatment (Pondclass) (0.0065 and 0.0056, respectively). Low daily fish gains were observed in the 50 and 75 kg treatments. Low dissolved oxygen and high total ammonia were concentrations resulted in low weight gains and condition indices of fish in the 50 and 75 kg treatments. Extrapolated fish yields corresponded to 6,205, 4,563, 3,686, 4,869 kg/ha/year for control, 50 kg, 75 kg and Pondclass treatments, respectively. The observed yields are comparable with field experiences in real ponds. The continuously adjusted treatment showed the lowest manure conversion ratio (3.85) in the fertilized treatments. The nitrogen content of rabbit excreta varied according to rabbit size, presence or absence of urine plus water waste, and food droppings. Urine plus water waste provided 28 % of the total nitrogen content in rabbit excreta, whereas food droppings provided 12 %. Rabbit urine may play an important role in aquacultural systems because it contains a large fraction of nitrogen in inorganic forms which are readily utilized for algal growth. Other rabbit excreta characteristics such as buoyancy may be advantageous in aquacultural systems. Rabbit excreta is a potentially rich source of fertilizer for use in fish ponds. / Graduation date: 1992