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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Studies of Cosmic Ray Composition using a Hybrid Fluorescence Detector

Simpson, Kenneth Mark January 2001 (has links)
This thesis describes several aspects of cosmic ray composition studies using the Utah Fly's Eye and High Resolution Fly's Eye (HiRes) detectors. The Fly's Eye detector utilises the atmospheric fluorescence technique to measure the development of cosmic ray cascades as they pass through the atmosphere. This is complementary to the surface array technique, as used by the Akeno experiment in Japan, which measures the electromagnetic and muon content of air showers at a single observation level. For some time it was thought that Fly's Eye and Akeno gave inconsistent composition results. In Chapter 4 I show that the inconsistency is due, for the most part, to a difference in the assumptions made about hadronic interactions. In Chapter 5 I present analysis of the composition between 10^17 and 10^18 eV using the prototype High Resolution Fly's Eye (HiRes) detector in coincidence with the Michigan Muon Array (MIA). The hybrid nature of these measurements gives us more information about cosmic ray showers than either technique on its own. The consistency or otherwise of the composition measured by the two detectors is discussed. Finally, in Chapter 6, I discuss a method of extracting the total proton-proton cross section from the cosmic ray data. This information is of interest because it is derived at centre of mass energies much higher (by at least an order of magnitude) than those currently accessible by collider experiments. I present a preliminary calculation of the cross section using the HiRes/MIA hybrid data set. / Thesis (Ph.D.)--Department of Physics and Mathematical Physics, 2001.
2

Studies of Cosmic Ray Composition using a Hybrid Fluorescence Detector

Simpson, Kenneth Mark January 2001 (has links)
This thesis describes several aspects of cosmic ray composition studies using the Utah Fly's Eye and High Resolution Fly's Eye (HiRes) detectors. The Fly's Eye detector utilises the atmospheric fluorescence technique to measure the development of cosmic ray cascades as they pass through the atmosphere. This is complementary to the surface array technique, as used by the Akeno experiment in Japan, which measures the electromagnetic and muon content of air showers at a single observation level. For some time it was thought that Fly's Eye and Akeno gave inconsistent composition results. In Chapter 4 I show that the inconsistency is due, for the most part, to a difference in the assumptions made about hadronic interactions. In Chapter 5 I present analysis of the composition between 10^17 and 10^18 eV using the prototype High Resolution Fly's Eye (HiRes) detector in coincidence with the Michigan Muon Array (MIA). The hybrid nature of these measurements gives us more information about cosmic ray showers than either technique on its own. The consistency or otherwise of the composition measured by the two detectors is discussed. Finally, in Chapter 6, I discuss a method of extracting the total proton-proton cross section from the cosmic ray data. This information is of interest because it is derived at centre of mass energies much higher (by at least an order of magnitude) than those currently accessible by collider experiments. I present a preliminary calculation of the cross section using the HiRes/MIA hybrid data set. / Thesis (Ph.D.)--Department of Physics and Mathematical Physics, 2001.
3

Vývoj HPLC-FLD metody pro stanovení žlučových kyselin ve žluči myší / The Development of HPLC-FLD Method for the Determination of the Bile Acids in the Bile of Mice

Kacerovská, Veronika January 2017 (has links)
Aim of the master thesis was the development and the optimization of the HPLC method with fluorescence detection for the determination of the bile acids in the bile of mice. On the basis of literature, the HPLC-FLD method has been proposed and optimized for the quantification of eight bile acids (cholic acid, glycocholic acid, deoxycholic acid, glycodeoxycholic acid, chenodeoxycholic acid, glycochenodeoxycholic acid, α-muricholic acid, and λ-muricholic acid) in the biological material. 1,2-benzo-3,4-dihydrocarbazole-9-ethyl-p-toluenesulfonate is suitable derivatization reagent for labeling of the bile acids. The calibration dependences, limits of detection and quantification (in the range of 0.88-1.78 μmol dm -3 ) for all bile acids are measured. In the biological sample five bile acids have been successfully identified and then determined (cholic acid, glycocholic acid, glycodeoxycholic acid, glycochenodeoxycholic acid, and α-muricholic acid). Key words: bile acids, HPLC, fluorescence detector, derivatization reaction, bile
4

A polarization isolation method for measurement of fluorescence assays in a microfluidic system using organic electronics for application to point-of-care diagnostics

Banerjee, Ansuman January 2008 (has links)
No description available.
5

Determination of fumonisins in maize by High Performance Liquid Chromatography with fluorescence and ultraviolet detection of o-phthaldialdehyde, naphthalene-2,3-dicarboxaldehyde and dansyl chloride derivatives

Ndube, Ncediwe January 2011 (has links)
Fumonisins, carcinogenic mycotoxins produced by various Fusarium species, occur naturally in maize and maize-based food products. They are hazards for animal and human health as they cause cancer in rodents and have been associated with oesophageal cancer and neural tube defects in humans. The most abundant naturally occurring fumonisins analogues in maize are fumonisin B1, B2 and B3 (FB1, FB2 and FB3). For analytical determination, they mostly require suitable extraction, clean-up and pre or post-column derivatization together with reversed-phase HPLC separation. o- Phthaldialdehyde (OPA) had been adopted as the most widely used derivatization reagent for fumonisins as they lack useful chromophores or fluorophores. Alternative derivatization reagents, naphthalene-2,3- dicarboxaldehyde (NDA) and dansyl chloride (DnS-Cl), were investigated in this study
6

Determination of fumonisins in maize by High Performance Liquid Chromatography with fluorescence and ultraviolet detection of o-phthaldialdehyde, naphthalene-2,3-dicarboxaldehyde and dansyl chloride derivatives

Ndube, Ncediwe January 2011 (has links)
Fumonisins, carcinogenic mycotoxins produced by various Fusarium species, occur naturally in maize and maize-based food products. They are hazards for animal and human health as they cause cancer in rodents and have been associated with oesophageal cancer and neural tube defects in humans. The most abundant naturally occurring fumonisins analogues in maize are fumonisin B1, B2 and B3 (FB1, FB2 and FB3). For analytical determination, they mostly require suitable extraction, clean-up and pre or post-column derivatization together with reversed-phase HPLC separation. o- Phthaldialdehyde (OPA) had been adopted as the most widely used derivatization reagent for fumonisins as they lack useful chromophores or fluorophores. Alternative derivatization reagents, naphthalene-2,3- dicarboxaldehyde (NDA) and dansyl chloride (DnS-Cl), were investigated in this study
7

Determination of fumonisins in maize by High Performance Liquid Chromatography with fluorescence and ultraviolet detection of o-phthaldialdehyde, naphthalene-2,3-dicarboxaldehyde and dansyl chloride derivatives

Ndube, Ncediwe January 2011 (has links)
Masters of Science / Fumonisins, carcinogenic mycotoxins produced by various Fusarium species, occur naturally in maize and maize-based food products. They are hazards for animal and human health as they cause cancer in rodents and have been associated with oesophageal cancer and neural tube defects in humans. The most abundant naturally occurring fumonisins analogues in maize are fumonisin B1, B2 and B3 (FB1, FB2 and FB3). For analytical determination, they mostly require suitable extraction, clean-up and pre or post-column derivatization together with reversed-phase HPLC separation. o- Phthaldialdehyde (OPA) had been adopted as the most widely used derivatization reagent for fumonisins as they lack useful chromophores or fluorophores. Alternative derivatization reagents, naphthalene-2,3- dicarboxaldehyde (NDA) and dansyl chloride (DnS-Cl), were investigated in this study. / South Africa

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