The aim of the thesis is to determine the influence exerted by the heads of the Catechetical School (Didaskaleion) in Alexandria on the growth and development of Christianity in Africa prior to the Arab invasion in 642 CE in Egypt. The methodological tool used is the Historical Method. Chapter 1 contains a discussion of the founding and development of the city of Alexandria through its Golden Era and until the Arab invasion in 642 CE. This city played an important role in the development of Christianity as it is there that the early Christians (the "followers of Christ's teachings") settled and established their faith. Chapter 2 deals with the founding of the Didaskaleion as an addition to the other big schools/"universities" in the city, for example the Musaion (also called the Museion), the Serapium (also called the Serapeum) and the Sebastion. All the possible heads of the School are discussed in order to get a full picture of the School and her activities during the time. In Chapter 3 all the extant and lost documents written by the heads of the School are discussed to provide insight into the formation of the Theology of the School and the contributions of her various heads. Chapter 4 constitutes the pinnacle of the thesis and depicts the influence of the School on the known parts of Africa – to the west and the south of Alexandria – during the first seven centuries CE (until the Arab invasion in 642). The influence is described at two levels: Influence, where mentioned by a specific writer, is called factual influence and includes personal influence. • Influence that is not mentioned but observed, is called derived influence. As there is ample evidence that the (heads of the) School exerted both factual and derived influence on the people in Africa, the conclusion can be drawn that the School and her heads played a significant role in the growth and development of Christianity in Africa. / Christian Spirituality, Church History and Missiology / D.Th. (Church history)