A series of five studies were conducted to examine the effect of exercise on selected pulmonary function measurements. Studies I and II determined the effect of an acute bout of exercise on various lung volumes immediately post-exercise and over a 24-hour post-exercise period. There were significant mean increases of 210 ml (20.6%) and 260 ml (20.8%) in the 5-minute post-exercise residual volume (RV) measurement for studies I and II, respectively. There also were significant mean increases of 170 ml (3.4%) and 190 ml (2.7%) in the 5-minute post-exercise total lung capacity (TLC) for studies I and II, respectively, while vital capacity (VC) remained unchanged. RV and TLC remained significantly increased over the pre-exercise values through 30 and 15 minutes of recovery, respectively. Studies III through V were undertaken to determine the physiological mechanism underlying the responses reported in studies I and II. In study III, transthoracic electrical impedance (TEI) was significantly decreased below the pre-exercise value through 30-minutes of recovery, indicating that there was an increase in thoracic fluid volume following exercise. However, TEI measurements alone cannot separate between intra- and extravascular fluid shifts. Therefore, studies IV and V attempted to identify whether the decrease in TEI and increase in RV reported in study III were due to intra- or extravascular fluid shifts. Study IV examined the TEI, RV, and TLC responses before and following exercise, as central blood volume (CBV) was experimentally increased via G-suit inflation, and decreased via venous occlusion tourniquets. The results suggest that RV is relatively insensitive to intravascular volume shifts within the thorax. Study V determined and followed the effect of an acute bout of exercise on lung diffusion capacity (D(,Lco)). D(,Lco)/V(,A) did not increase significantly following exercise, suggesting that the decrease in TEI following exercise is the result of extravascular fluid accumulation. It was concluded that a sub-clinical pulmonary edema occurs following exercise. A logical sequence of events based on the results of studies I through V was proposed as a possible explanation for the responses of RV and TLC following exercise.

A dissertation submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in part fulfilment of the requirements for the degree Master of Medicine in Internal Medicine. 1993. / Normal thyroid physiology and pathophysiOlogy with reference to non-thyroidal illness is reviwed, including infections, specific disease states and drugs and their effects on thyroid function tests. A review of the literature reveals that following almost any infection the serum T4 and T3 decrease as a result of diminished secretion of TSH and thyroxine, accelerated T4 disappearance, inhibition of hormone binding to transport proteins and decreased peripheral T4 to T3 conversion. [Abbreviated Abstract. Open document to view full version] / AC2017

Thesis--M. Phil., University of Hong Kong, 1986.

Thesis (M.S.)--Ohio State University, 2009. / Title from first page of PDF file. Includes vita. Includes bibliographical references (p. 125-128).

No description available.

Clinically, the modified Bruce protocol is widely used to predict functional capacity in cardiac patients. However, it has been suggested that cardiac patients have lower oxygen uptakes for standard workloads. In order to study this, we measured oxygen uptake (V02) and venous bloodV02 derived from lactic acid concentration during a modified Bruce treadmill protocol in 12 pest myocardial infarction (MI) and 12 normal males. During three stages of the protocol mean oxygen uptake was significantly lower (1.42 - 6.2 ml/kg.min; p < .001) for the pest MI than the normal males.However, venous blood lactic acid concentrations were not different at these stages. The MI patients' measured V02 for three stages of the protocol ranged from 1.8 - 7.3 ml/kg.min lower than the Bruce predictions for cardiacs. In addition, measured V02 (max) for cardiac patients were from 3.68 to 11.15 ml/kg.min lower than the predicted the normal subjects. These data suggest myocardial damage may slow oxygen kinetics and results in lower actual V02during treadmill testing. However, blood lactic acid concentrations failed to demonstrate an anaerobic compensation for the lower V02 in pest MI patients.

The intent of this study was to compare the rate of gastric emptying of three commercially available athletic drinks (GA, BT, and BP) against water, and in doing so to assess the exchange of water, carbohydrate and electrolytes 15 minutes after ingestion. Nine men and three women reported to the laboratory after having fasted for 12 hours.' A No. 20 French Levine Tube was inserted through the nasal passage and into the stomach. The subjects drank down 400 ml of the test solution containing 25 mg of phenol red which was used as a volume indicator. Fifteen minutes after ingestion, the gastric contents were aspirated via the tube by means of a 50 ml syringe. The 4 conditions were tested in one morning, with the order of feedings rotated between subjects. The recovered gastric contents were measured for total volume, volume of original drink, carbohydrate content and gastric electrolyte exchange. Student t values were used to test the difference between means set at the P < .05 level of confidence. BT and BP were found to empty statistically the same volume of fluid in 15 minutes as did water, while GA emptied 39% less volume than did water. BT, BP, and GA contributed 1.9, 4.5 and 6.8 gm of carbohydrate respectively in 15 minutes. These data are in agreement with previous findings that high glucose concentrations (GA - 4.5 gam) cause a slowing of gastric emptying.

Typescript. / Thesis (Ph. D.)--University of Hawaii at Manoa, 1979. / Bibliography: leaves 86-97. / Microfiche. / xii, 97 leaves ill. 29 cm

Thesis (MAppSc in Pharmacy)--University of South Australia, 1996

Thesis (MAppSc) -- University of South Australia, 1998