During the Leukocytapheresis (LCAP) process used to treat patients suffering from acute Ulcerative Colitis, medical practitioners have to continuously monitor the Hematocrit (Ht) level in the blood to ensure it is within the acceptable range. The work done, as a part of this thesis, attempts to create an early warning system that can be used to predict if and when the Ht values will deviate from the acceptable range. To do this we have developed an algorithm based on the Group Method of Data Handling (GMDH) and compared it to other Neural Network algorithms, in particular the Multi Layer Perceptron (MLP). The standard GMDH algorithm captures the fluctuation very well but there is a time lag that produces larger errors when compared to MLP. To address this drawback we modified the GMDH algorithm to reduce the prediction error and produce more accurate results. / by Jay Thakkar. / Pagination error. "References" should be leaves 63-67, and pagination end with leaf 67. / Thesis (M.S.C.S.)--Florida Atlantic University, 2011. / Includes bibliography. / Electronic reproduction. Boca Raton, Fla., 2011. Mode of access: World Wide Web.

Design of intelligent systems that can learn from the environment and adapt to the change in the environment has been pursued by many researchers in this age of information technology. The Group Method of Data Handling (GMDH) algorithm to be implemented is a multilayered neural network. Neural network consists of neurons which use information acquired in training to deduce relationships in order to predict future responses. Most software tool during the simulation of the neural network based algorithms in a sequential, single processor machine like Pascal, C or C++ takes several hours or even days. But in this thesis, the GMDH algorithm was modified and implemented into a software tool written in Verilog HDL and tested with specific application (XOR) to make the simulation faster. The purpose of the development of this tool is also to keep it general enough so that it can have a wide range of uses, but robust enough that it can give accurate results for all of those uses. Most of the applications of neural networks are basically software simulations of the algorithms only but in this thesis the hardware design is also developed of the algorithm so that it can be easily implemented on hardware using Field Programmable Gate Array (FPGA) type devices. The design is small enough to require a minimum amount of memory, circuit space, and propagation delay. / by Mukul Gupta. / Thesis (M.S.C.S.)--Florida Atlantic University, 2010. / Includes bibliography. / Electronic reproduction. Boca Raton, Fla., 2010. Mode of access: World Wide Web.