External nuclear medicine diagnostic imaging of early primary and metastatic lung cancer tumors is difficult due to the poor sensitivity and resolution of existing gamma cameras. Nonimaging counting detectors used for internal tumor detection give ambiguous results because distant background variations are difficult to discriminate from neighboring tumor sites. This suggests that an internal imaging nuclear medicine probe, particularly an esophageal probe, may be advantageously used to detect small tumors because of the ability to discriminate against background variations and the capability to get close to sites neighboring the esophagus. The design, theory of operation, preliminary bench tests, characterization of noise behavior and optimization of such an imaging probe is the central theme of this work. The central concept lies in the representation of the aperture shell by a sequence of binary digits. This, coupled with the mode of operation which is data encoding within an axial slice of space, leads to the fundamental imaging equation in which the coding operation is conveniently described by a circulant matrix operator. The coding/decoding process is a classic coded-aperture problem, and various estimators to achieve decoding are discussed. Some estimators require a priori information about the object (or object class) being imaged; the only unbiased estimator that does not impose this requirement is the simple inverse-matrix operator. The effects of noise on the estimate (or reconstruction) is discussed for general noise models and various codes/decoding operators. The choice of an optimal aperture for detector count times of clinical relevance is examined using a statistical class-separability formalism.

The purpose of this investigation was to study the radiations of the 169/Tm nucleus as it de-excites after the electron capture decay of the 169/Yb. Numerous unreported gammas were present in the sample. The origins of these gamma rays were found.

The purpose of this investigation was to attempt to resolve the energy levels of Cs133 that can be excited by inelastic scattering of 14 Mev neutrons.

<p>Gamma ray spectroscopy has provided enormous amounts of information on the behaviour and structure of atomic nuclei [SHA88, BEA92, EBE08]. Most of the major discoveries in experimental nuclear physics over the last five decades are strongly associated with improvements in detector technologies. Inorganic scintilators led to the discovery in 1963 of the first excited states of a rotational band based on the ground state of 162Dy. Improvements in peak-to-background ratios and detector resolutions obtained with germanium led to the first evidence of backbending which is associated with a two quasi-particle excitation in 162Dy [SHA88]. More recently the development of composite and highly-segmented Ge detectors has significantly increased the performance and power of detection systems. The Clover detector is such a detector system and is in use at iThemba LABS. This study concerns the evaluation of the particle transport code MCNPX 2.5.0 as a tool to model complex composite detectors such as the Clover. Lanthanum silicate (LSO) and Lead tungstate (PbWO) are also evaluated as possible suppressor shield materials. It is shown that reasonable agreement between experiment and simulation is found when the experiment is accurately reproduced. However, when complex detection modes are implemented in the detector based on the number of elements that fire, MCNPX cannot be used to model the detector performance exactly. Differences between simulated and experimental results are found in suppressed add-back mode. It is proposed that the discrepancies are due to limitations in implementation of the pulse-height and special anti-coincidence tally in MCNPX. LSO and PbWO are compared to BGO as suppressor shield materials. It is found that LSO is not an ideal material for a suppression shield. PbWO is shown to give performance values similar to that of BGO. The back-plug is shown to have no effect on the Peak-to-Total ratio but is effective at reducing the background at lower energies.</p>

Thesis (M. Phil.)--University of Hong Kong, 2001. / Includes bibliographical references (leaves [86]-88).

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published_or_final_version / Physics / Master / Master of Philosophy

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