Spelling suggestions: "subject:"gene mapping"" "subject:"ene mapping""
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Development of bovine type I genetic markers and their application in investigation of the trypanotolerance traitKasigwa, Morris Agaba January 1996 (has links)
No description available.
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Molecular genetics of human arylamine N-acetyl transferasesMatas, Nada January 1996 (has links)
No description available.
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Physical and genetical investigation of the Xp11.3 region on the short arm of the human X-chromosome.Wittwer, Pia Ethena January 2004 (has links)
The pattern of inactivation in the DXS8237E-UBE1-PCTK1 region is of particular interest, since the mechanisms of X chromosome inactivation and the escape from inactivation are, as yet, not fully understood. The inactivation status of the DXS8237E and PCTKl gene differ: the first undergoes normal inactivation and the second escapes this process. The status of the UBEl gene has been controversial, although it is widely excepted that it does escape X chromosome inactivation. Physical mapping of the region employing YACs and subsequently P ACs has been undertaken, but was restricted in scope by the high frequency of rearrangements occurring. DNA sequences between DXS8237E, UBE1, PCTKl and the distal gene, UHX1, have been investigated with regard to LINEI elements, which are thought to playa role in X-inactivation. The results obtained strongly suggest a link between LINE1 elements and X chromosome inactivation. Sequence analysis results also contributed to the understanding of difficulties with restriction mapping of the region. Further, this work includes the first reported establishment of the UBEl exonintron boundaries. Additionally, genomic sequence analysis showed that only 46kb separate DXS8237E from UHX1, which confirms that this region is extremely gene rich.
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Mapping of clouston hidrotic ectodermal dysplasiaKibar, Zoha D. January 1999 (has links)
No description available.
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A high-resolution genetic map of human chromosome 16 and localization of the MEF gene / by Yang Shen.Shen, Yang, 1953- January 1994 (has links)
Copies of author's previously published articles inserted. / Includes bibliographic references. / vii, 200, [74] leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Addresses a need for more highly informative markers to be placed on high density cytogenetic-based physical and genetic linkage maps of chromosome 16. / Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, Women's and Children's Hospital, 1994
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Simple sequence repeat marker development and mapping in cultivated sunflower, Helianthus annuus L.Yu, Ju-Kyung 07 September 2001 (has links)
The cultivated sunflower (Helianthus annuus L., x=17) is one of the most important
annual oilseed crops in the world. There are very few publicly shared sequence-based
DNA markers and genetic maps in sunflower, even though molecular DNA markers
and genetic maps have become widely used in all areas of genetic research and
breeding in plant species. The objectives of this study were to develop sequence-based
molecular markers and utilize the markers for genetic analyses and constructing
maps in the cultivated sunflower. A total of 131 functional simple sequence repeat
(SSR) markers were developed for 16 elite inbred lines using a small insert genomic
library enriched for short simple sequence repeats. The polymorphism information
content (PIC) estimated from 74 polymorphic SSR markers ranged from 0.0 to 0.93
with mean value of 0.55. Tetranucleotide repeats were significantly more
polymorphic than dinucleotide and trinucleotide repeats, and no obvious correlation
was found between repeat numbers and PIC scores. Genetic distance among 16 inbred lines, estimated from 74 polymorphic SSR markers ranged 0.175 to 0.543. Principal
coordinate and cluster analyses of the genetic distance matrix well explained the
difference between oilseed lines and confectionery lines, and sterility maintainer lines
and fertility restorer lines. A total of 1,090 SSR markers were screened for
polymorphism between the parents of two mapping populations. The two genetic
maps were constructed by genotyping 94 recombinant inbred lines from a cross
between PHA and PHB (276 SSR loci covering 1377.4 cM with mean distance of 4.99
cM), and 94 F��� progeny from a cross between HA370 and HA372 (122 SSR loci
integrated into the existing RFLP framework map covering 1348.0 cM with mean
distance of 6.77 cM). Ninety-three percent of the SSR markers were mapped to single
loci and 56.5% of the loci were co-dominant. Clustering of SSR loci was observed
near centromeric regions and most of the distorted loci were mapped to centromeric or
distal regions. A concerted effort to develop SSR markers and generate highresolution
SSR maps will enhance future fingerprinting analyses, fine-scale genome
analyses and molecular breeding in the cultivated sunflower. / Graduation date: 2002
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A comparison of simulated annealing and genetic algorithms for the genome mapping problemsGunnels, John A. 10 August 1993 (has links)
The data used for the construction of genome maps is imperfect, therefore the
mapping of a physically linear structure must take place in a very uneven feature space.
As the number of genes to be ordered grows, it appears to be impractical to use
exhaustive search techniques to find the optimal mapping. In this paper we compare
genetic algorithms and simulated annealing, two methods that are widely believed to
be well-suited to non-smooth feature spaces, and find that the genetic algorithm
approach yields superior results. Here we present performance profiles of comparable
implementations of both genetic algorithms and simulated annealing. We have
translated the problem to a form comparable to the shortest-path problem and found
that the ability of a genetic algorithm to combine different partial solutions seems to be
responsible for its superiority over the simulated annealing method. This is because in
the genome mapping problem, as in the Traveling Salesman Problem, good solutions
tend to be rather sparse and because optimal subtours tend to be components of nearly
optimal tours. / Graduation date: 1994
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Computational analysis of structure and function of genomic sequencesSingh, Abanish. January 2008 (has links)
Thesis (Ph.D.) -- University of Texas at Arlington, 2008.
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Phylogenetic relationships in Secale and PCR-based EST mapping in wheat /Chikmawati, Tatik, January 2003 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2003. / Typescript. Vita. Includes bibliographical references (leaves [128]-144). Also available on the Internet.
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Phylogenetic relationships in Secale and PCR-based EST mapping in wheatChikmawati, Tatik, January 2003 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2003. / Typescript. Vita. Includes bibliographical references (leaves [128]-144). Also available on the Internet.
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