- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 141 to 150 of 17485 (0.036 seconds)Spelling suggestions: "subject:"genetics"" "subject:"kenetics""
| 141 |
Factors Associated with Genetic Counselors’ Explicit Attitudes Toward Lesbian, Gay, Bisexual, and Transgender IndividualsBaker, Josie Marie 05 October 2021 (has links)
No description available.
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| 142 |
Adeno-associated virus vectors-mediated gene therapies for inherited neuromuscular diseasesShang, Qifan 28 January 2022 (has links)
Inherited neuromuscular diseases are a group of disorders that affect skeletal muscle or neuronal control of the skeletal muscle. Due to the incredible clinical and genetic heterogeneity of these disorders, very few curative therapies are available. Affected patients often require lifetime treatments to manage their symptoms and a great number of them succumb to premature deaths due to respiratory failures. Recent development in gene therapy, especially Adeno-Associated Virus (AAV) vectors provide exciting avenues for curing monogenic neuromuscular diseases by delivering a functional copy of the defective gene into the musculature. This review covers recent progress made to implement AAV vectors as a viable treatment option for inherited neuromuscular diseases including advancements in engineering technologies for AAV vector optimization, promising results from preclinical animal studies and clinical trials. Current obstacles to clinically translate AAV gene replacement therapy are further discussed.
In conclusion, AAV-based gene therapy serves as an ideal treatment to correct the genetic defects underlying inherited neuromuscular diseases with recent regulatory approvals as the basic and translational science proves safe and effective. Further understanding of AAV vector mechanisms and advancements in capsid engineering are needed to build a stronger foundation to establish AAV vector-mediated gene replacement therapy as a standard treatment option clinically to treat inherited neuromuscular diseases.
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| 143 |
Investigating the Role of Condensin II/CAP-D3 in the Maintenance of Cellular HomeostasisDeutschman, Emily 23 May 2019 (has links)
No description available.
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| 144 |
Assessing the General Public’s View of Direct-to-Consumer (DTC) Genetic Testing and Their Interpretation of DTC Website Disclaimer MessagesRuehl, Madison 07 October 2020 (has links)
No description available.
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| 145 |
Impact of previous genetic counseling and objective numeracy on accurate interpretation of a pharmacogenetics test reportDrelles, Kelly Ann 30 September 2020 (has links)
No description available.
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| 146 |
Characterizing Huntington’s Disease (HD) Patients Based on Parental HDVicini, Leah Marie 08 October 2020 (has links)
No description available.
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| 147 |
A model of natural selection based on a mathematical theory of guessing.Warburton, Frederick. E. January 1963 (has links)
No description available.
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| 148 |
Experimental and clinical approaches to the biology of congenital defect.Miller, James. R. January 1959 (has links)
No description available.
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| 149 |
The genetics and physiology of susceptibility to the teratogenic effects of cortisone in mice.Kalter, Harold. January 1953 (has links)
No description available.
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| 150 |
Genetico-embryological studies on normal and cleft palates in mice.Walker, Bruce. E. January 1954 (has links)
No description available.
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