The primary aim of this thesis is to construct explicit examples of four dimensional hyperbolic link complements. Using the theory of Kirby diagrams and Kirby calculus we set up a general framework that one can use to attack such a problem. We use this framework to construct explicit examples in a smooth standard S⁴ and a smooth standard S² x S². We then characterise which homeomorphism types of smooth simply connected closed 4-manifolds can admit a hyperbolic link complement, along the way giving constructions of explicit examples.