The broad objective of the study was to determine and validate medicinal plants used by resource-limited farmers to control internal and external parasites in goats in the Eastern Cape Province, South Africa. A survey was conducted among 50 farmers and three herbalists to determine medicinal plants used to control parasites in goats. The survey revealed nine plant species belonging to eight families that were used. Among the identified plant species, Aloe ferox, Acokanthera oppositifolia and Elephantorrhiza elephantina were the plants having the highest Fidelity Level for their use, each scored 100.00 percent, followed by Albuca setosa (83.33 percent). These plants were then selected for validation studies. Gas-Chromatography-Mass-Spectrometry (GC-MS) revealed 7, 33, 26 and 32 bioactive phytochemicals in A. ferox, E. elephantina, A. oppositifolia and A. setosa, respectively. Terpenes and fatty acids were present, oxygenated terpenes being the most abundant hydrocarbons present in all the four plant species. The effect of acetone, methanol and ethanol extracts of leaves of Aloe ferox and Acokanthera oppositifolia on tick repellency and acaricidal activity were investigated on blood engorged Ambylomma hebraeum and Rhipicephalus decoloratus ticks at concentration 15, 30 and 50 percent. The 30 and 50 percent acetone extract of A. ferox and Dazzel dip had the highest acaricidal properties of 100 percent. The 50 percent methanol extract of A. oppositifolia and 50 percent acetone extract of A. ferox had the highest repellency activity of 89 percent and 85.33 percent, respectively. Results from this study revealed that the efficacy of medicinal plants used by farmers to control ticks vary with the type of solvent used for extracting the bioactive compounds. Furthermore, it revealed that Aloe ferox and A. opppositifolia plant extracts possess repellent and acaricidal activities. In a study to investigate the anthelminthic effect of crude extracts of Elephantorrhiza elephantina and Albuca setosa plants, significant anthelminthic effect on nematodes was observed in both plants. In this study, all E. elephantina and A. setosa extracts caused paralysis and mortality. Methanol was the most effective solvent in extracting bioactive compounds and methanol extract showed the best anthelminthic effects among the crude extracts investigated in both plants. The least time taken for the worms to be paralysed was 8.33 mins and 14.33mins in 100mg/ml methanol extracts of E. elephantina and A. setosa, resepectively. Methanol extract of E. elephantina and A. setosa (100mg/ml) had the highest anthelminthic activity and mortality was recorded after 18mins and 20mins, respectively. Results from this study revealed that these two plants possess anthelminthic activities. The study revealed that resource-limited farmers use medicinal plants to control internal and external parasites in goats. Gas-Chromatography-Mass-Spectrometry analysis showed that these plants contain bioactive compounds that have a potential in controlling parasites. Validation studies showed that A. ferox and A. oppositifolia possess repellent and acaricidal activities whereas A. setosa and E. elephantina possess anthelminthic activities.

Small-scale goat farmers from south-western KwaZulu-Natal Province, South Africa, identified gastrointestinal helminths, dry-season feed scarcity and poor reproductive performance as major production constraints and highlighted the paucity of information on goat health and management. The research and extension processes adopted to address these problems comprised on-station experimentation, followed by on-farm validation combined with the participatory dissemination of both study findings and relevant information on goat health care. The approach included the use of the FAMACHA© system to assess anaemia, a characteristic symptom of infection with the gastrointestinal nematode, Haemonchus contortus (Rudolphi, 1803). On-station experimentation indicated that urea-molasses block supplementation during the dry, winter season was a cost-effective option. Unfortunately, when tested on-farm, the value of such supplementation proved inconclusive, possibly due to low block consumption and further research into alternative and palatable protein supplements for goats is suggested. However, tactical anthelmintic treatment with ivermectin effectively reduced faecal egg counts and is recommended, as is concurrent symptomatic anthelmintic treatment, as determined by the FAMACHA© system, since this practice appeared to improve reproductive capacity. Investigations to better adapt the FAMACHA© system to goats is, however, recommended. A flexible training framework was developed with the collaboration of the farmers, providing them with advice on goat health and management. This ‘hands-on’ approach encompassed regular meetings geared to the farmers’ current expertise and exploited the on-farm experimentation as a training vehicle. The process nurtured local farmer ‘champions’, strengthened the extension skills of researchers and technicians and incorporated the development of a Goatkeepers’ animal health care manual. Indications are that the use of such an approach has considerable potential for the development of goat farming. Moreover this process, which is relatively novel for South Africa, is equally applicable to other similar agro-ecological zones. Access to veterinary and agricultural inputs in areas where communal grazing is practised could be vastly improved and a case is made for universities, researchers, extensionists and farmers to collaborate to encourage the long-term sustainable development of these communities. / Thesis (Ph.D.)-University of KwaZulu-Natal, Pietermaritzburg, 2007.

Feeding of lespedeza to sheep and goats, besides supplying protein, could be a possible alternative remedial control measure against gastro-intestinal parasites in sheep and goats. However, the feeding behaviour of individual animals and their feed intake are likely to influence t its effect on the parasites. This study was conducted to determine the different feeding behaviour of sheep and goats on Sericea lespedeza and its effect on faecal egg count. The first part dealt with behaviour of animals feeding on lespedeza or leucaena within the rangeland while for parasitic response they were fed on lespedeza or veld hay. During feeding behavior, three sheep and three goats averaged 2- 3 years of age were observed for 30 days during the months of March and April 2006. Activities such as browsing, grazing and idling were recorded after every two minutes for every animal while following animals at a distance of five meters. Feed intake was determined by recording the number of bites made by each animal for a period of ten minutes and by estimating the weight of forage eaten. More (P<0.001) browsing time was observed on goats at both lespedeza and leucaena plot than on sheep, with goats consistently spending longer time browsing than sheep on both lespedeza and leucaena than sheep between 7.00 and 14.00h. More of the browsing time of goats was spent on leucaena than on lespedeza. The longest time of grazing by animals was on the lespedeza plot than on leucaena plot, with sheep grazing for a longer (P<0.001) time than goats. The biggest difference in grazing time for sheep at the lespedeza and leucaena occurred during morning hours. Animal type and interaction of feed animal type significantly affected idling time with goats Idling for a longer (P<0.001) time than sheep at both the lespedeza and leucaena plots. Feeding rate (bite/min) for both sheep and goats were similar on both lespedeza and leucaena plots. Intake rates were higher (P<0.01) for both sheep and goats on leucaena than on lespedeza, with sheep having higher (P<0.01) intake rates than goats on both plots. Animals had the fastest bite rate and intake rate during midday (12.00h) and lowest rates at 14.00h. The highest intake rate occurred on leucaena in the morning and afternoon, but lower than lespedeza during midday. For parasites response twelve sheep and twelve goats aged between 3 and 4 years were used in a study that lasted 60 days. Animals were naturally infested by gastro-intestinal parasites. Egg count was done according to McMaster egg count technique (Ministry of Agriculture, Fisheries and Food, 1977) by magnifying parasitic eggs from faecal samples dissolved in saturated sodium chloride. During feacal egg count, the effect of animal on feed intake was highly significant (P<0.001) with sheep consuming more of each kind of feed (lespedeza or hay) than goats. Live weight of animals decreased during the early period of feeding, beyond which it remained stable. Egg count varied significantly (P = 0.015) among periods of sampling, a general trend indicating a decrease from day 0 to day 46 beyond which egg count tended to increase. When regression analysis was done to determine the effect of the previous week’s intake, it was observed that increased intake during the previous week was associated with depression in egg count, the effect attaining significance (P<0.05) for both sheep and goats on hay and for sheep on lespedeza. The results of this study are rather inconclusive about the effect of supplementing small ruminants with Sericea lespedeza hay on gastro-intestinal parasites, owing to variation associated with intake of lespedeza and hay, thus warranting further investigation. / Thesis (M.Sc.)-University of KwaZulu-Natal, Pietermaritzburg, 2008.

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