Thesis (M. Med. Sc.)--University of Hong Kong, 2002. / Includes bibliographical references (leaves 58-63).

Thesis (Ph. D.)--University of Hong Kong, 2004. / Also available in print.

Thesis (M.Med.Sc.)--University of Hong Kong, 1999. / Includes bibliographical references (leaves 32-36). Also available in print.

Thesis (M.Med.Sc.)--University of Hong Kong, 2001. / Includes bibliographical references (leaves 42-53). Also available in print.

Thesis (M.Med.Sc.)--University of Hong Kong, 2002. / Includes bibliographical references (leaves 58-63). Also available in print.

Thesis (M. Med. Sc.)--University of Hong Kong, 2006.

Background: Green tea is rich in catechin, a polyphenolic antioxidant. Consumption of green tea or extract from green tea has been shown to result in weight loss, increased fat oxidation, and elevated energy expenditure in mice and humans. Green tea consumption has also been shown to result in increased exercise endurance in mice and improved maximal oxygen uptake (VO2max) in humans. It is not clearly known whether green tea consumption would increase exercise endurance in humans. Objective: The aim of this study was to determine if the daily consumption of decaffeinated green tea extract for 4-5 weeks, would improve exercise endurance in humans, as measured by running 2.5 miles on an indoor track. Subjects, Design, and Methods: This study was based on a randomized, double-blind design. Fourteen, normal, healthy individuals volunteered for participation and completed the study. They were divided into two groups (n= 7 for each group). All participants completed 2 endurance trials, 1 at the baseline and 1 at the conclusion of the study. Each trial consisted of a 2.5 mile run around the GSU Recreation Center indoor track. One group consumed green tea extract pill containing 900 mg catechins and the other group consumed a placebo for 4-5 weeks between run trials. Results: Green tea and placebo groups improved their running times, however, there was no significant difference between these two groups in mean end time (P = 0.74). Under one statistical analysis, the green tea group significantly improved their running time compared to baseline (P = 0.019), while the placebo group did not. However, under another statistical analysis (removing one participant due to possible skewing effect), both groups significantly improved their running time over baseline (P< 0.05). Conclusions: This study was not able conclusively ascertain whether or not the daily consumption of green tea improved endurance performance as measured by 2.5 mile run times. Results of this study should be used with caution due to small sample size. Future studies are warranted on the impact of green tea consumption on exercise endurance, using a longer duration and a larger sample size than has been studied.

Thesis (M.S.)--University of Texas at El Paso, 2009. / Title from title screen. Vita. CD-ROM. Includes bibliographical references. Also available online.

Abstract available on the file 00front / Thesis (PhD (Plant Production and Soil Science))--University of Pretoria, 2006. / Plant Production and Soil Science / unrestricted

The present study was carried out to examine the chemopreventive effects of curcumin and green tea polyphenols on the hamster cheek pouch carcinogenesis model. This model of oral carcinogenesis has been widely used in chemoprevention studies, however, these studies have been limited to the use of DMBA as the carcinogenic agent. We have developed a protocol of carcinogenesis in the hamster cheek pouch using B[a]P, a broadly distributed environmental carcinogen, formed as a by-product of the combustion of organic materials including cigarette smoke. B[a]P- induced tumors in the hamster cheek pouch are primarily endophytic squamous cell carcinomas that closely resemble squamous cell carcinomas of the human oral mucosa. The cheek pouch of male Syrian hamsters were treated topically for eight weeks with 0.6% curcumin, 6.0% curcumin, 2.5% green tea polyphenols, or 5.0% green tea polyphenols, 3 times per week 30 minutes prior to the application of 2.0% B[a]P. The animals were sacrificed 24 hours and 72 hours after the last treatments. Short-term mechanistic markers of malignant progression were used to determine effects of each compound. Cellular proliferation, assessed by bromodeoxyuridine (Brdu) incorporation, p53 protein accumulation, and apoptotic activity were evaluated. The results of the present study demonstrated that 0.6% curcumin and 2.5% green tea polyphenols had strong inhibitory effects on cellular proliferation and p53 protein accumulation. And 6.0% curcumin and 5.0% green tea polyphenols appeared to induce apoptosis. Our data suggest that curcumin and green tea polyphenols may have a plausible chemopreventive effect on oral carcinogenesis in the hamster cheek pouch model.