The breeding of the guinea pig in Bolivia has always been important for the inhabitants of rural areas. Nevertheless, in recent years there has been broader acceptance for consumption of the guinea pig in the urban middle class, beginning to grow the market of the meat of guinea pig in the Departamentos of Bolivia, because the good flavor and high degree of nutrition of this meat, therefore offering a good option to improve nutrition in the diet of Bolivians. Currently the type of breeding found of the valleys of Bolivia in the great majority of the communities is family-based, with essentially native and mixed-breed animals that have good characteristics of resilience and rapid maturation but with low yield with respect to the weight of the carcass. The producer has basic know-how of some aspects of the breeding; however, this is not sufficient to optimize of production and to achieve greater yields. In the Project of Genetic Improvement and Management of the guinea pig in Bolivia (MEJOCUY), through the course of several years of the investigation into the genetic improvement of guinea pigs, has achieved the establishment of two populations of meat production for different bioclimatic conditions of Bolivia: the MEJOCUY population and the Tamborada population. Nevertheless, the productive performance in field conditions by both populations is as yet unknown, for which reason the need arises to evaluate these yields to identify which of them presents better results and to offers the producer a population that adapts best to field conditions and can obtain better benefits. Therefore, the objectives of the given work were the following: GENERAL OBJECTIVE To compare the productive yield in guinea pigs of the two populations of meat production in field conditions and MEJOCUY research barns. SPECIFIC OBJECTIVES To compare the productive yield of guinea pigs in family breeding of the High Valley of the Departamento of Cochabamba with the productive yield in the Project MEJOCUY research barns. To quantify weight gain per animal in the stages of lactation and adolescent development of the populations MEJOCUY and Tamborada under field conditions and at Project MEJOCUY research barns. HYPOTHESIS Ha: The productive yield of the populations MEJOCUY and Tamborada is greater in the Project MEJOCUY research barns with regard to the performance of the same in field conditions. Ho: The productive yield of the populations MEJOCUY and Tamborada is similar in field conditions with respect to the sheds of the project MEJOCUY.