Thesis (M.S.)--University of Montana, 2006. / Mode of access: Internet. Title from title screen. Description based on contents viewed Dec. 6, 2006. Includes bibliographical references (p. 156-160).

Thesis (MPhil (Industrial Psychology. Africa Centre for HIV/AIDS Management))--University of Stellenbosch, 2011. / ENGLISH ABSTRACT: The researcher conducted an explorative, qualitative study to identify the perceptions and experiences of stigma and discrimination among people living with HIV and AIDS in order to establish strategies within ARV Clinic to deal with the situation and eliminate this as a barrier to access the services. The study population included 5 men and 5 women who access health services at Oshakati ARV Clinic and have been on ARVs for more than one year, aged 20-60 years old. The study participants were selected using a purposive sampling approach and interviewed in the ARV clinic. The study found that participants have experienced enacted and internal stigma and discrimination related to their HIV status within their community and families. They however did not perceive or report any experiences of stigma and discrimination in the ARV clinic. Possibility exists that the participants might not be well empowered to detect acts of stigma and discrimination in the health care environment. / AFRIKAANSE OPSOMMING: Die navorser het 'n verkennende, kwalitatiewe studie uitgevoer om die waarnemings en ervarings van stigma en diskriminasie tussen mense wat met MIV en VIGS leef, vas te stel met die doel om strategieë te bepaal binne die ARV kliniek om die situasie te hanteer en die hindernes om dienste te bekom te verwyder. Die studiepopulasie het bestaan uit 5 mans en 5 vroue wat die gesondheidsdienste van die Oshakati ARV kliniek gebruik en wat ARV’S vir meer as een jaar gebruik en tussen die ouderdomme van 20-60 jaar is. Die deelnemers is gekies met 'n doelgerigte steekproeftrekking-benadering en onderhoude is gevoer in die ARV-kliniek. Die studie het bevind dat die deelnemers interne stigma en diskriminasie wat verband hou met hul MIV-status binne hul gemeenskap en families ondervind het. Hulle het egter nie aangedui dat hulle stigma en diskriminasie ervaar het by die ARV-kliniek nie. Die moontlikheid bestaan dat die deelnemers nie goed bemagtig is om dade van stigma en diskriminasie in gesondheidsdienste te kan identifiseer nie.

Thesis (M.Sc. (Physiology)) -- University of Limpopo, 2021 / The purpose of this study was to investigate the effect of cART on renal function and assess the association between renal function and cardiovascular risk factors in a black rural HIV-positive population in Limpopo Province, Mankweng district. We have conducted a cross-sectional study which included both male and female cART-treated patients (n=84), cART-naïve patients (n=27) and HIV-negative controls (n=44). We have measured biomarkers of renal function (plasma cystatin C, clusterin, retinol binding protein 4 [RBP4]) and determined the estimated glomerular filtration rate (eGFR) using the chronic kidney disease-epidemiology collaboration formula (CKD-EPI). We have also measured blood pressure (BP), body mass index (BMI) and fasting blood glucose (FBG). The prevalence of renal dysfunction was similar among the study groups. A significant difference in RBP4 was found among the groups after controlling for covariates (age, gender, alcohol consumption, BMI, systolic blood pressure and FBG) (F (2, 146) = [4.479], p=0.010). The significant difference in RBP4 was specifically observed between the cART-treated and cART-naïve groups (p=0.008). Cystatin C, clusterin and eGFR were not significantly different among the study groups after controlling for the covariates. The cardiovascular risk factors age (β=0.207; p=0.039), CD4+ T-cell count (β=-0.236; p=0.040), and duration of cART (β=0.232; p=0.043) were independently associated with cystatin C. The use of cART independently associated with RBP4 (β=0.282; p=0.004). Age (β=-0.363; p=0.001), CD4+ T-cell count (β=0.222; p=0.034) and duration of cART (β=-0.230; p=0.034) independently associated eGFR. Renal dysfunction is common in this HIV-positive population, with similar rates as the HIV-negative population. Plasma cystatin C as a promising alternative renal biomarker need to be re-evaluated in this HIV-positive population. RBP4 may be a more promising renal function biomarker in the HIV-positive population. Cardiovascular risk factors are associated with renal dysfunction in this rural HIV-positive population and CD4+ T-cell count may be an independent predictor for renal function.