No

Yes / This article is an editorial for the special focus theme issue on “hair research” published by the Experimental Dermatology journal. Here we introduce the articles from the special issue and pose a few questions. The full list of publications for the hair research special issue is available on the Journal’s web site. Many of the articles can be viewed free of charge on the web site. This is for; Experimental Dermatology, Volume 29, Number 3, published March 2020.

No / Cyclosporine A (CsA) has long been recognized as a potent hair growth stimulator in both humans and rodent. The induction of a dose-dependent hypertrichosis is one of the most frequent adverse effects of long-term CsA therapy (Lutz, 1994). However, it is unclear how this immunosuppressant induces hypertrichosis in patients or stimulates hair growth in human scalp skin transplanted on nude mice (Gilhar et al., 1988; Gilhar et al., 1991).

Typescript (photocopy). / Digitized by Kansas Correctional Industries

The aim of this study was to investigate the influence of soft tissue decomposition on the stability of drugs incorporated in hair antemortem. Two burial trials were conducted: in the first trial, rats were administered oxycodone over five days; in the second trial, rats were administered heroin over nine days then drug abstinent for another nine days. After each respective treatment the rats were sacrificed and buried in controlled burial microcosms. Concentrations of oxycodone and selected metabolites or the metabolites of heroin; 6-monoacetylmorphine and morphine, incorporated within rat hair and liver were measured before and during the decomposition process. Oxycodone was analysed in hair and liver samples, while morphine and 6-monoacetylmorphine were analysed in hair samples by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Oxycodone concentrations in both hair and liver decreased as the interment period and decomposition of the carcasses progressed. 6-Monoacetylmorphine was not detected in any hair samples collected from the exhumed carcasses. / UOIT

Skin-derived precursors (SKPs) are multipotent dermal stem cells that reside within a hair follicle niche and that share properties with embryonic neural crest precursors. Here, we have asked whether SKPs and their endogenous dermal precursors originate from the neural crest or whether, like the dermis itself, they originate from multiple developmental origins. To do this, we used two different mouse Cre lines that allow us to perform lineage tracing: Wnt1-cre, which targets cells deriving from the neural crest, and Myf5-cre, which targets cells of a somite origin. By crossing these Cre lines to reporter mice, we show that the endogenous follicle-associated dermal precursors in the face derive from the neural crest, and those in the dorsal trunk derive from the somites, as do the SKPs they generate. Despite these different developmental origins, SKPs from these two locations are functionally similar, even with regard to their ability to differentiate into Schwann cells, a cell type only thought to be generated from the neural crest. Analysis of global gene expression using microarrays confirmed that facial and dorsal SKPs exhibit a very high degree of similarity, and that they are also very similar to SKPs derived from ventral dermis, which has a lateral plate origin. However, these developmentally distinct SKPs also retain differential expression of a small number of genes that reflect their developmental origins. Thus, an adult neural crest-like dermal precursor can be generated from a non-neural crest origin, a finding with broad implications for the many neuroendocrine cells in the body.

Skin-derived precursors (SKPs) are multipotent dermal stem cells that reside within a hair follicle niche and that share properties with embryonic neural crest precursors. Here, we have asked whether SKPs and their endogenous dermal precursors originate from the neural crest or whether, like the dermis itself, they originate from multiple developmental origins. To do this, we used two different mouse Cre lines that allow us to perform lineage tracing: Wnt1-cre, which targets cells deriving from the neural crest, and Myf5-cre, which targets cells of a somite origin. By crossing these Cre lines to reporter mice, we show that the endogenous follicle-associated dermal precursors in the face derive from the neural crest, and those in the dorsal trunk derive from the somites, as do the SKPs they generate. Despite these different developmental origins, SKPs from these two locations are functionally similar, even with regard to their ability to differentiate into Schwann cells, a cell type only thought to be generated from the neural crest. Analysis of global gene expression using microarrays confirmed that facial and dorsal SKPs exhibit a very high degree of similarity, and that they are also very similar to SKPs derived from ventral dermis, which has a lateral plate origin. However, these developmentally distinct SKPs also retain differential expression of a small number of genes that reflect their developmental origins. Thus, an adult neural crest-like dermal precursor can be generated from a non-neural crest origin, a finding with broad implications for the many neuroendocrine cells in the body.

This paper provides the theoretical component to a blog I wrote as part of an academic program in Cultural Studies for a period from March 2, 2011 until September 30, 2011. Called The Last Triangle: Sex, Money and the Politics (http://www.thelasttriangle.com), I set out to explore the increasing normalization of pubic hair removal among women in North America. The reasons for the upswing in the popularity of pubic hair removal are hard to pinpoint, but seem to be motivated by a number of forces. From the ready accessibility of pornography, where pubic hair is currently so rare it has spawned its own fetish, to the widespread attention Brazilian waxing has received in the media, pubic hair removal is merely one among a myriad of body grooming practices many women increasingly indicate they feel obliged follow. This paper will explore some of those ideas, taking a critical view of the practice in light of questions around performing femininity, how pubic hair removal pertains to body control, and how pubic hair removal is, for many, increasingly viewed as a practice closely connected with good hygiene. Because it is intimately tied to the purchase of dedicated products, pubic hair removal will also be considered in as much as it relates to capitalism. Because the blog was a fundamental component of my research experience, excerpts of both my own writing, as well as comments from readers, will be included in conversation here with the theoretical questions. / Thesis (Master, Cultural Studies) -- Queen's University, 2011-10-14 09:54:11.802

This single case study conducted with creative interviews, addresses perceptions of professional norms and meanings of black female hairstyles in Swedish public administration. By incorporating prior U.S scholarship and applying intersectional theory, black female hair is analyzed through social constructions of gender, race and class as intermeshed dimensions. This study indicates how the norms of neutrality, disadvantage black female employees in Swedish public administration, as they are subjected to stares, comments and touching of their "deviant" hairstyles. The intersectional analysis indicates how perceptions of femininity and blackness collide in problematic ways, as black professional hair is described as straight hair. Despite this, the informants were convinced that straight hair does not come naturally for black women. Concluding, this study suggests that black women may be more seriously taken, by presenting a "feminine" and "neutral" hairstyle, through subjecting themselves to perceived straight hair norms in Swedish public administration

Thesis (PhD)--University of South Australia, 2003.