Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Diagnostic Radiography, Department of Nursing and Radiography in the Faculty of Health Wellness Sciences at Cape Peninsula University of Technology 2014 / Aim: The aim of this study was to record the values of CTDIw and DLP displayed on the Computed Tomography (CT) scanner monitors of patients undergoing CT examinations of the head as Diagnostic Reference Levels (DRL) for dose optimisation in Northern Nigeria. Background: A brain CT scan is the most common CT examination performed, and this modality is recognized as delivering a high dose. CT, therefore, contributes significantly to the total collective effective dose to the population. Elimination of unnecessary or unproductive radiation exposure is necessary. To achieve this, practitioners must adhere to the principles of the justification of practices, and optimisation of radiation protection. Furthermore, the development of DRLs for the local context is advised. These reference doses are a guide to the expected exposure dose from a procedure and are useful as an investigation tool to identify incidences where patient doses are unusually high. Methodology: The study was conducted in three radiology departments with CT centres in Northern Nigeria. Data was collected, using a purposive sampling technique, from 60 consenting adult participants (weighing 70 ±3 kg) that had brain CT scans on seventh generations 4&16-slice GE and 16-slice Philips CT scanners. Prior to commencement of the study the CT scanners were certified by the medical physicists. For each brain scan, patient information, exposure factors, weighted computed tomography dose index (CTDIw), volume computed tomography dose index (CTDIvol) and dose length product (DLP) values were recorded. The data were analysed using SPSS version (16) statistical software. The mean, standard deviation and third quartile values of the CTDIw and DLP were calculated. An inter-comparison of the measured doses from the three research sites was conducted. A combined dose for the three centres was calculated, and compared with the reported data from the international communities where there are established DRLs. Results: The mean CTDIw and DLP values were: centre A (88 mGy and 713 mGy.cm), centre B (68 mGy and 1098 mGy.cm), and centre C (70 mGy and 59 mGy.cm). Comparison of CTDIw and DLP for the scanners of the same manufacturers showed statistically significant differences (p=0.003) and (p=0.03) respectively. In the case of the scanners of a different model but the same number of slices, the comparison of DLP was statistically significant (p=0.005) while no significant difference was noted in the measured CTDIw. Third quartile values of the cumulative doses of CTDIw and DLP, for Northern Nigeria were determined as 77 mGy and 985 mGy.cm respectively. Conclusion: The study has established Local DRLs (LDRLs) which are significantly higher than most of the reported data in the literature. Also dose variation between centres was noted. Optimization is thus recommended. Keywords: Head Imaging, Radiation Dose, Dose optimization, Computed Tomography, Local Diagnostic Reference Levels, Radiation Protection