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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
101

Misconduct-Related Discharge from Active Duty Military Service: An Examination of Precipitating Factors and Post-Deployment Health Outcomes

Brignone, Emily 01 May 2017 (has links)
U.S. military service members who are discharged from service for misconduct are at high risk for mental health and substance use disorders, homelessness, mortality, and incarceration. The purpose of this dissertation was to investigate the pre- and post-discharge experiences and characteristics of this highly vulnerable population in order to inform improved prevention and intervention strategies. Administrative data from the Department of Defense and Veterans Health Administration for veterans of recent conflicts were used to conduct 3 related retrospective cohort studies. These included (1) an evaluation of the demographic and military service characteristics and service-connected disabilities associated with discharge for misconduct; (2) an examination of post-discharge health status and healthcare utilization among misconduct-discharged veterans; and (3) the development of predictive models for homelessness and mortality among misconduct-discharged veterans. Several demographic and military service characteristics were associated with increased risk for misconduct discharge, as were exposure to sexual trauma, and post-discharge designation of service-connected disabilities related to mental illness. Misconduct-discharged veterans were found to have significant and complex healthcare needs, and used clinical services at approximately double the rate of routinely discharged veterans. Several risk factors for homelessness and mortality among this population were identified. Risk stratification models showed good predictive accuracy for homelessness, and fair predictive accuracy for mortality. Targeted counter-attrition strategies and an increased focus on health-related determinants of misconduct, including rehabilitative approaches to behavioral problems, may help to reduce misconduct-related attrition. Efforts to transition post-discharge care from specialty settings to integrated primary care settings may be successful in mitigating adverse outcomes. Risk stratification techniques can facilitate the efficient targeting of resources.
102

The Impact of the Veterans Health Administration's Home Based Primary Care on Health Services Use, Expenditures, and Mortality

Castora-Binkley, Melissa 31 March 2015 (has links)
Background: Among patients with multiple chronic conditions, care coordination and integration remains one of the major challenges facing the U.S. health care system. A home-based, patient-centered primary care program has been offered through the Veterans Health Administration (VHA) since the 1970s for frail veterans who have difficulty accessing VHA clinics. The VHA Home Based Primary Care (VHA HBPC) aims to integrate primary care, rehabilitation, disease management, palliative care, and coordination of care for frail individuals with complex, chronic diseases within their homes. Early research suggested that VHA HBPC was associated with positive outcomes (e.g., reduced resource use and patient satisfaction). However, evidence regarding the effect of the VHA HBPC program on health services use (especially hospital and nursing home use), expenditures, and other patient outcomes remains limited. The present study is designed to fill this gap as the rise in the number of veterans with complex health care needs will likely increase in the coming decades. Objectives: The current study aimed to examine the impact of VHA HBPC on health services use, expenditures, and mortality among a cohort of new VHA HBPC enrollees identified in the national VHA data system. The specific aims of this study were: 1) to examine the effect of VHA HBPC on major health service use (hospital, nursing home, and outpatient care) paid for by the Veterans Administration; 2) to examine the effect of VHA HBPC on total health services expenditures; and 3) to examine whether VHA HBPC enrollees experienced similar mortality and survival as compared to a matched concurrent cohort. Methods: This study used a retrospective cohort design. A new VHA HBPC enrollee cohort (the treatment group) and a propensity matched comparison cohort (the comparison group) were identified from VHA claims in fiscal years (FY) 2009 and 2010 and were followed through FY 2012. Data on health service use, expenditures, and mortality/survival data were obtained via the VHA administrative datasets (i.e., Decision Support System, Purchased Care, and Vital Status Files). Propensity scores of being enrolled in the VHA HBPC were generated by a logistic regression model controlling for potential confounders. After 41,244 matched pairs were determined adequate through several diagnostic methods, means tests, relative risk analyses, and generalized linear models were used to estimate the effect of VHA HBPC on outcomes. Additionally, a Cox proportional hazards regression model was used to estimate the effect of VHA HBPC on survival. Subgroup analyses were conducted stratifying by age (85 and older), comorbidities (2 or more), and the receipt of palliative care. Based on the results of the original analyses, a series of sensitivity analyses were conducted that modified the described sample selection criteria and matching algorithm. Results: Analyses of the original cohort revealed that VHA HBPC patients had significantly higher risks of being admitted into a hospital (RR 1.53, 95% CI 1.51-1.56) or nursing home (RR 1.65, CI 1.50 - 1.81). The average total expenditures during the study period were significantly higher for the VHA HBPC group as compared to the control group ($85,808 vs. $44,833, respectively; p < .001). In terms of mortality and survival, VHA HBPC enrollees had higher mortality (RR 1.45, CI 1.43 - 1.47), and shorter survival (HR 1.89, CI 1.86 - 1.93) as compared to those in the comparison group. Subgroup analyses found that these relationships generally remained when stratified by age 85 or older or having two or more comorbidities. However, for those who received palliative care, VHA HBPC participants had significantly lower risk of VHA hospitalization overall (RR 0.84, CI 0.81 - 0.87) and immediately prior to death. Finally, exploratory post-hoc analysis suggested that VHA HBPC recipients were at higher risk of VHA hospitalization at 30 (RR 1.11, CI 1.06 - 1.16), 60 (RR 1.16, CI 1.11 - 1.20), and 90 days (RR 1.16, 1.12 - 1.21) prior to death relative to the comparison group. After selecting only those that had a baseline hospitalization and refining the matching algorithm to account for time to death and additional comorbidities, VHA HBPC participants who had been enrolled in the program for at least six months had lower risks for hospital (RR 0.89, CI 0.88 - 0.90) and nursing home admissions (RR 0.74, CI 0.67 - 0.81). However, total expenditures remained significantly higher among those in VHA HBPC relative to the comparison group ($89,761 vs. $85,371, respectively; p < .001). Discussion: This study found that without accounting for important covariates such as initial hospitalization, time to death, and a range of comorbidities, VHA HBPC was associated with higher health service use, higher expenditures, higher mortality, and shorter survival as compared to a similar group of patients not receiving VHA HBPC. After accounting for these factors, VHA HBPC was associated with a lower risk of nursing home use, and after six months, VHA HBPC was associated with lower risk of both nursing home and hospital use. These findings suggest that while VHA HBPC may improve quality of life and patient satisfaction through patient-centered integrated primary care, it may not generate cost savings for the healthcare system. Future research is needed to understand variation in program implementation and how this affects the impact of VHA HBPC on service use and cost.
103

Elective Early Term Delivery and Adverse Infant Outcomes in a Population-Based Multiethnic Cohort

Salemi, Jason Lee 26 March 2014 (has links)
The length of human pregnancy, arguably the most natural of physiological processes, is undergoing subtle but consequential modification in order to adapt to modern societal demands. The gestational age distribution of births in the United States has been shifting to lower gestational ages over the past two decades, parallel to a concomitant rise in obstetrical intervention in pregnancy. The result has been an increase in elective deliveries at 37-38 weeks (early term). A population-based retrospective cohort study of over 616,000 live-born full-term singleton infants was conducted to investigate the association between elective early term delivery and subsequent infant morbidity, mortality, and health care utilization in the first year of life. Data were examined from a statewide, multi-year, clinically-enhanced database created by linking birth certificate records to maternal and infant hospital discharge records, and to infant death certificates, for all infants born to Florida-resident mothers from 2005-09. All infants delivered to mothers with an established medical condition that could have justified early delivery were excluded from the study, as it would not be possible to determine if an early delivery in those cases was elective or medically-necessary. Based on the timing and reason for delivery initiation, the study population was categorized into four exposure groups: 1) early electively induced delivery at 37-38 weeks (EED-I), 2) early elective cesarean delivery at 37-38 weeks (EED-CS), 3) early spontaneous delivery at 37-38 weeks (ESD), 4) early medically-indicated delivery at 37-38 weeks (EID). The comparison group consisted of all expectantly managed infants who were full term deliveries (FTD) at ≥39 weeks. Adverse infant outcomes in the first year of life included respiratory morbidities, neonatal sepsis, feeding difficulties, admission to the neonatal intensive care unit, the frequency and duration of hospital encounters, and infant mortality. Multivariable generalized linear mixed models were used to estimate odds ratios (OR) or rate ratios (RR) and 95% confidence intervals (CI) between exposure and each outcome, adjusting for maternal, infant, and hospital characteristics and accounting for the correlation among infants born at the same facility. Infants who were delivered by EED-I or EED-CS comprised 13% of the study population, and 40% of infants born in the early term period. Infants who were delivered by EED-I experienced the lowest likelihoods of respiratory morbidities, neonatal sepsis, and admission to the NICU when compared to FTD infants. In contrast, infants delivered by EED-CS had significantly increased risks several adverse birth outcomes, with magnitudes ranging from a 9% to 40% increase. Only 8.3% of all infants were re-admitted to the hospital after birth. Despite having the lowest likelihood of the birth morbidities studied, infants delivered by EED-I had a small 10-15% increased odds of being re-hospitalized in the first year of life, compared to FTD infants. These infants also had a slightly higher mean number of visits and combined LOS during post-birth hospitalizations, although the absolute differences from other exposure groups was small. Elective early term cesarean infants actually had a slightly lower risk of re-hospitalization, particularly re-hospitalizations that occurred between weeks 3-52 of life. Neonatal and post-neonatal deaths were rare events (0.3 and 1.3 deaths per 1,000 live births, respectively) in this comparatively low-risk study population. There were no differences in survival when comparing the EED-I and EED-CS groups to the FTD group. The results of this study raise the concern that these public health efforts to reduce elective early term inductions have been based on biased evidence from a limited number of studies in which artificially elevated risks for early electively-induced infants were reported. In stark contrast to the current dogma, this study found that when a methodologically appropriate comparison group was used (i.e., expectant management), elective induction prior to 39 weeks was NOT associated with an increased risk of any adverse infant outcomes in early life. In contrast, our findings do support the avoidance of purely elective cesarean sections prior to 39 weeks in lieu of expectant management. The evidence presented in this large, methodologically-sound study should caution against a general avoidance of ALL elective early term deliveries, and foster support for continued research in this still relatively new arena.
104

Towards Improved Medication Use : Increasing Understanding of Professional Efforts

Björkman, Ingeborg January 2006 (has links)
<p>Professionals and researchers have developed a number of strategies aimed at improving the quality and safety of medication use. However, studies continue to demonstrate persistent problems. For instance, the first paper in this thesis reveals the prevalence of potentially harmful drug combinations among elderly people in Europe. The following four papers focus on two professional groups and how they have approached safety and quality issues related to medication use: 1) the Swedish drug and therapeutics committees (DTCs) and 2) pharmacist involved in pharmaceutical care, an international movement. Qualitative research approaches were applied.</p><p>Papers II and III focus on the DTCs: analyses indicate a development of the perception of the DTC role over time. The focus of the activities was broadened – from targeting prescribing physicians to incorporating decision-makers and patients. However, a clear patient-centered perspective was generally lacking. Moreover, the findings indicate a shift in focus from cost aspects of medication use to an increased focus on quality and safety aspects. </p><p>In the studies addressing pharmaceutical care (Papers IV and V), the findings propose that different classification systems for drug-related problems had different characteristics which reflected differences in goals in the pharmaceutical care process. It was also found that the concept of pharmaceutical care was understood in different ways and that the perceptions were based on at least two different understandings of health and illness. First, a patient-centered perspective characterized by a <i>holistic</i> understanding of health and illness, and, second, an “EBM perspective” primarily based on a <i>biomedical</i> understanding of health and illness. </p><p>This thesis has disclosed new aspects of how two groups of professionals perceive their work towards improved quality and safety of medication use. A patient-centered perspective among healthcare collectives is not obvious; therefore, efforts and comprehensive strategies supporting change are necessary. Strategies should focus on challenging the traditional thought patterns and care approaches among professionals and students. </p>
105

Towards Improved Medication Use : Increasing Understanding of Professional Efforts

Björkman, Ingeborg January 2006 (has links)
Professionals and researchers have developed a number of strategies aimed at improving the quality and safety of medication use. However, studies continue to demonstrate persistent problems. For instance, the first paper in this thesis reveals the prevalence of potentially harmful drug combinations among elderly people in Europe. The following four papers focus on two professional groups and how they have approached safety and quality issues related to medication use: 1) the Swedish drug and therapeutics committees (DTCs) and 2) pharmacist involved in pharmaceutical care, an international movement. Qualitative research approaches were applied. Papers II and III focus on the DTCs: analyses indicate a development of the perception of the DTC role over time. The focus of the activities was broadened – from targeting prescribing physicians to incorporating decision-makers and patients. However, a clear patient-centered perspective was generally lacking. Moreover, the findings indicate a shift in focus from cost aspects of medication use to an increased focus on quality and safety aspects. In the studies addressing pharmaceutical care (Papers IV and V), the findings propose that different classification systems for drug-related problems had different characteristics which reflected differences in goals in the pharmaceutical care process. It was also found that the concept of pharmaceutical care was understood in different ways and that the perceptions were based on at least two different understandings of health and illness. First, a patient-centered perspective characterized by a holistic understanding of health and illness, and, second, an “EBM perspective” primarily based on a biomedical understanding of health and illness. This thesis has disclosed new aspects of how two groups of professionals perceive their work towards improved quality and safety of medication use. A patient-centered perspective among healthcare collectives is not obvious; therefore, efforts and comprehensive strategies supporting change are necessary. Strategies should focus on challenging the traditional thought patterns and care approaches among professionals and students.
106

The Quality of Surgical Care for Radical Cystectomy in Ontario from 1992 to 2004

Kulkarni, Girish Satish 20 January 2009 (has links)
This thesis is composed of three studies pertaining to the quality of care for radical cystectomy in Ontario between 1992 and 2004. In the first paper, the associations between provider volume and both operative and overall mortality were assessed. In the second paper, potential factors that could explain the association between volume and outcome were explored. In the final paper, the impact of waiting for cystectomy on survival outcomes was evaluated. Methods: A total of 3296 patients undergoing cystectomy for bladder cancer in Ontario between 1992 and 2004 were identified using the Canadian Institute for Health Information Discharge Abstract Database and the Ontario Cancer Registry. The effects of hospital and surgeon volume on operative mortality and overall survival were assessed using random effects logistic regression and marginal Cox Proportional Hazards modeling, respectively. To elucidate the factors underlying the volume-outcome association, the ability of a number of structure and process of care variables to attenuate the impact of volume was assessed. The effect of waiting for care, from transurethral resection to cystectomy, on overall survival was also assessed using marginal Cox models. Results: Neither hospital nor surgeon volume was significantly associated with operative mortality; however, both were associated with overall mortality. Of the measured structure/process measures, hospital factors caused the greatest attenuation of the volume hazard ratios, albeit to a limited degree. The wait time between the decision for surgery and cystectomy was also significantly associated with overall survival. The impact of delayed care was greatest for patients with lower stage disease. The data suggested a maximum wait time of 40 days for cystectomy. Conclusions: In this thesis, gaps in the quality of care for radical cystectomy in Ontario were identified. Patients treated by low volume hospitals and surgeons or those with long wait times all experienced worse outcomes. Since the underlying measures responsible for provider volume remain elusive, additional work is required to understand what these factors are. Initiatives to decrease wait times, however, are under way in Ontario. Whether these interventions decrease wait times and benefit patients remains to be seen.
107

Development and Testing of an Instrument to Measure the Quality of Children’s End-of-life Care from the Parents’ Perspective

Widger, Kimberley Ann 31 August 2012 (has links)
Background: The Senate of Canada asserts that quality end-of-life care is the right of every Canadian. Yet, little is known about the quality of end-of-life care for dying children and their families. Purpose: The study purpose was to develop and test an instrument to measure parents’ perspectives on the quality of care provided to families before, at the time of, and following the death of a child. Methods: In study Phase I, key components of quality pediatric end-of-life care were synthesized through a systematic review of research literature then validated and extended through focus groups with bereaved parents. In Phase II, instrument items were developed to assess structures, processes, and outcomes important to quality end-of-life care, then tested for content and face validity by health professionals and bereaved parents. In Phase III, the instrument was administered to bereaved mothers from across Canada and psychometric testing conducted. Results: Instrument items were developed based on review of 67 manuscripts and 3 focus groups with 10 parents. The Content Validity Index for the instrument was 0.84 as assessed by 7 health professionals. The instrument was assessed by 6 bereaved parents for face and content validity as well as their cognitive understanding of the items. In the final phase, 128 mothers completed the instrument and 31 of those completed it twice. Initial evidence for test-retest reliability, internal consistency, and construct validity was demonstrated for 7 subscales: Connect with Families, Involve Parents, Share Information with Parents, Share Information among Health Professionals, Support Parents, Provide Care at Death, and Provide Bereavement Follow-up. Additional items with demonstrated content validity only were grouped into three domains: Support the Child, Support Siblings, and Structures of Care. Implications: This study is a significant step forward in comprehensive measurement of the quality of children’s end-of-life care. The instrument provides a mechanism for feedback to health professionals, health systems, and policy makers to improve care provided to families facing the death of a child.
108

Stroke Services in Ontario- based Long- Term Care Homes

Hellings, Chelsea 08 December 2011 (has links)
There is limited information regarding the provision of rehabilitation services in long-term care (LTC) to meet the needs of residents living with stroke. This project assessed service availability within Ontario-based homes and examined the relationship between service comprehensiveness and functional outcome for residents with rehabilitation potential. The first phase involved survey development and distribution to a sample of homes to assess comprehensiveness. The second phase linked survey findings and administrative data to determine whether comprehensiveness (measured using an index score derived from survey responses) was correlated with change in functional status using linear regression modeling. There was marked variability in service comprehensiveness across responding homes (n=32 of 154 homes; 21%). No significant linear correlation was shown between comprehensiveness and change in ADL function (n=178). Although our study failed to show an association, rehabilitation should be considered an important aspect of LTC programming and should adhere to practice standards where possible.
109

Stroke Services in Ontario- based Long- Term Care Homes

Hellings, Chelsea 08 December 2011 (has links)
There is limited information regarding the provision of rehabilitation services in long-term care (LTC) to meet the needs of residents living with stroke. This project assessed service availability within Ontario-based homes and examined the relationship between service comprehensiveness and functional outcome for residents with rehabilitation potential. The first phase involved survey development and distribution to a sample of homes to assess comprehensiveness. The second phase linked survey findings and administrative data to determine whether comprehensiveness (measured using an index score derived from survey responses) was correlated with change in functional status using linear regression modeling. There was marked variability in service comprehensiveness across responding homes (n=32 of 154 homes; 21%). No significant linear correlation was shown between comprehensiveness and change in ADL function (n=178). Although our study failed to show an association, rehabilitation should be considered an important aspect of LTC programming and should adhere to practice standards where possible.
110

Development and Testing of an Instrument to Measure the Quality of Children’s End-of-life Care from the Parents’ Perspective

Widger, Kimberley Ann 31 August 2012 (has links)
Background: The Senate of Canada asserts that quality end-of-life care is the right of every Canadian. Yet, little is known about the quality of end-of-life care for dying children and their families. Purpose: The study purpose was to develop and test an instrument to measure parents’ perspectives on the quality of care provided to families before, at the time of, and following the death of a child. Methods: In study Phase I, key components of quality pediatric end-of-life care were synthesized through a systematic review of research literature then validated and extended through focus groups with bereaved parents. In Phase II, instrument items were developed to assess structures, processes, and outcomes important to quality end-of-life care, then tested for content and face validity by health professionals and bereaved parents. In Phase III, the instrument was administered to bereaved mothers from across Canada and psychometric testing conducted. Results: Instrument items were developed based on review of 67 manuscripts and 3 focus groups with 10 parents. The Content Validity Index for the instrument was 0.84 as assessed by 7 health professionals. The instrument was assessed by 6 bereaved parents for face and content validity as well as their cognitive understanding of the items. In the final phase, 128 mothers completed the instrument and 31 of those completed it twice. Initial evidence for test-retest reliability, internal consistency, and construct validity was demonstrated for 7 subscales: Connect with Families, Involve Parents, Share Information with Parents, Share Information among Health Professionals, Support Parents, Provide Care at Death, and Provide Bereavement Follow-up. Additional items with demonstrated content validity only were grouped into three domains: Support the Child, Support Siblings, and Structures of Care. Implications: This study is a significant step forward in comprehensive measurement of the quality of children’s end-of-life care. The instrument provides a mechanism for feedback to health professionals, health systems, and policy makers to improve care provided to families facing the death of a child.

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