The diploma thesis deals with the designing and assessment of two variants of the reconstruction of the air conditioning system for the half of 3rd floor laboratory building BioVendor – Laboratorní medicína a.s. company. The system is proposed to fulfil hygienic, operational, economic and functional requirements for indoor microclimate of laboratories. The task of this system is the transport of fresh air to interior and the covering of heat gains in summer. The equipment is also designed for the regulation of air humidity in the interior. The theoretical part deals with the application of heat penetration of solar radiation double glazed construction. Calculating and project part deals with the specific proposal of two variants of a new HVAC system-level studies of which the selected variant is developed as the project documentation. Experimental part is devoted to measuring of CO2 concentration in operationally similar laboratory. The result of this work is to evaluate the operational and economic impacts on the choice of technically feasible options and implementation documentation selected option. The benefit of the experiment is to verify sufficient air exchange to ensure the optimum concentration of carbon dioxide in laboratories.

The master´s thesis is about the design of heating and cooling of a multifunctional house. The building is functionally divided into parts of shops, administration and apartments. Thesis describes various cooling options and basic types and functions of air conditioning systems. Three variants of the system at the level for expanded building permits and their evaluation are developed. The selected variant is developed at the project level for the construction.

The first part of the thesis is aimed on creating internal microclimate of the hotel complex by air conditioning systems. The choice of systems is based on theoretical knowledge’s and practical application in abroad. In the second part there is designed solution for hotel apartments and conference hall. The other areas are designed only conceptual. Technical solutions of chosen systems are the main outcome of the thesis. In the third part there are published my experimental measurements from laboratories of Oulu University of Applied Sciences. For the study field of Air Conditioning has been chosen Air Flow Measurement and Test Operation of HVAC unit. For the study field of Renewable Energy has been chosen the Heat Pump and for study field of Refrigeration has been chosen Water Cooling and Chiller Box.