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Transcriptional regulation of Runx1 in the developing haematopoietic systemNottingham, Wade January 2007 (has links)
No description available.
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A study of the circulating myeloid progenitor cell in man /To, Luen Bik. January 1984 (has links) (PDF)
Thesis (M.D.)--University of Adelaide, 1985. / Includes bibliographical references (leaves 1-14 of section Reference).
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Spatial distribution pattern of murine CD34 mRNA+ cells in hematopoietic and lymphoid organs鄺懿珩, Kwong, Yi-hang, Agnes. January 1997 (has links)
published_or_final_version / Biochemistry / Doctoral / Doctor of Philosophy
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Mini-transplant of haematopoietic stem cells for the management of haematological and non-haematological diseases. / CUHK electronic theses & dissertations collectionJanuary 2006 (has links)
Allogeneic haematopoietic stem cell transplantation (HSCT) has been used successfully to treat children and adults with high-risk or relapsed hematopoietic malignancies, marrow failure syndromes, and hereditary immunodeficiency disorders. When initially developed, allogeneic HSCT was conceived as a method of rescuing patients from the toxic side effects of dose-intensive chemoradiotherapy. Due to transplant-related toxicities, the application of myeloablative allogeneic HSCT has been limited to younger patients without organ dysfunctions. Since the early 1990s many groups of investigators have explored strategies using less intensive preparative regimens that would allow engraftment of hematopoietic progenitor cells from either identical or non-identical donors. These reduced-intensity conditioning (RIC) regimens result in less tissue damage, less inflammatory cytokine secretion, and possibly lower rates of graft-versus-host disease (GVHD) and non-relapse mortality (NRM). Such non-myeloablative approach, or "mini-transplant", has been suggested to benefit older patients as well as in conditions in which traditional myeloablative conditioning regimens are associated with high rates of non-relapse mortality. / Allogeneic HSCT is the only curative therapy for many patients with myeloid malignancies or myelodysplastic syndrome (MDS). The development of reduced-intensity preparative regimens may allow the extension of this form of treatment to older and patients with coexisting medical illness. On the other hand, relapse after transplantation remains the most important cause of treatment failure in patients with refractory acute myeloid leukemia (AML) or MDS, and is associated with poor survival. Evaluation of prognostic factors may help to improve the results of myeloablative and RIC allogeneic HSCT in this group of patients. Furthermore, the impact of comorbidities on outcomes of RIC allogeneic HSCT in this group of patients with refractory AML or MDS needs to be defined. / The application of embryonic and adult stem cells in regenerative and reparative therapies of non-hematopoietic diseases is emerging rapidly. Human umbilical cord blood (UCB) is a rich source of hematopoietic stem cells and mesenchymal progenitor cells. Although clinical experience to date with UCB has focused on hematological application, early preclinical studies support the hypothesis that multipotential stem cells derived from UCB exhibit functional characteristics similar to that observed in adult marrow-derived stem cells in mediating vascular and organ regenerative capabilities. However, the application of these preclinical findings in clinical setting needs to be further studied. Mini-transplant of human UCB may be an effective approach to repair organ damage in patients with non-hematological diseases. / Wong Siu Ming Raymond. / Adviser: Joseph J.Y. Sung. / Source: Dissertation Abstracts International, Volume: 73-01, Section: B, page: . / Thesis (M.D.)--Chinese University of Hong Kong, 2006. / Includes bibliographical references (leaves 187-223). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
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Telomerase activity in human umbilical cord cell populations containing hematopoietic stem cellsMurthy, Vidya. January 2002 (has links)
Thesis (M.S.)--Worcester Polytechnic Institute. / Keywords: Hematopoietic stem cells; Umbilical cord blood. Includes bibliographical references.
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Exploring the complications of hematopoietic stem cell transplantation : a laboratory and clinical studyRobles, Joseph Delano January 2014 (has links)
abstract / Paediatrics and Adolescent Medicine / Doctoral / Doctor of Philosophy
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Late complications of haemopoietic stem cell transplantationSzeto, Ching-ho., 司徒精豪. January 2004 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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Human herpesvirus 6 infection after allogeneic stem cell transplantation /Wang, Fu-Zhang, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.
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HLA polymorphism : genomic typing and impact on unrelated stem cell transplantation /Aldener-Cannavá, Anna, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 6 uppsatser.
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Cell kinetics and residual damage /Trainor, Kevin James. January 1979 (has links) (PDF)
Thesis (M.Ag.Sci.)--University of Adelaide, Dept. of Animal Physiology,1980.
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