Objective: High Risk Reminder (HRR) system is the lately mobile application technology developed by Taipei Medical University of Medical Informatics Research Institute. The objective of HRR is to provide high risk patient test results such as lab, radiology, pathology to physician immediately by mobile short message and internet e-mail. The mobile short message is to provide abstract information to physician such as patient name, inpatient bed ward number, the abcdrmal test result. The physician can receive the latest patient’s abcdrmal test information at any place, time. Therefore, the physician can take intervention treatment as soon as possible for patient treatment. Moreover, the physician wants to know more detail the high risk patient’s information can open the e-mail to review the patient’s profile in order to provide treatment plan. The purpose of using the mobile and internet technology is to improve patient safety. The WF Teaching Hospital has using the HRR system to serve its patient and physician for 6 months. There are more than 600 mobile short messages and e-mail communication for physicians. To reach the patient safety goals is the critical mission of WF Hospital. Therefore, the evaluation of HRR patient safety contribution needs to analyze.。This study is introducing HRR system functions and evaluating HRR’s contribution.。This research is based on the empirical study. We investigate the HRR’s impaction to assist high risk patient severe test result information communication for physician to assist patient’s treatment for physician and hospital. Meanwhile, the two mobile short message and e-mail communication media which one is more effective for physician is analyzed also. Design: This study measures dimensions of information quality, system quality, use, user satisfaction, individual impact and organizational impact based on the D&M IS Success Model. Multivariate techniques were used to evaluate the relationships of the Model. Measurements: The dimensionality of each scale and degree of association of each item with the attribute of interest were determined by principal components factor analysis with orthogonal varimax rotation. The reliability of each resultant scale was computed using Cronbach’s alpha coefficient. Construct validity was examined through factor analysis and by correlation analyses. Multiple regression techniques were used to evaluate the relationship between the set of six dimensions and comparison of PHS and e-mail. Results: Physicians have using the HRR systems are the surveyors composed of this survey samples. There are 56 questionnaires had been distributed the physicians. Seven questionnaires are invalid due to rarely using the HRR system. The valid questionnaires are 85%。Of the respondents, 93% were male; 73% were undergraduate; 90% were primary physicians.。 From the research finding , the two communication medias of short message, and e-mail are positive relationships for effective and efficiency communication for physicians to assist high risk patient severe test result information delivery. The research two constructs of PHS and e-mails’ indicators are positive for improving better communication; The information quality for user’s effectiveness, satisfaction relationship impacts for users and organization. Comparison effective communication between PHS and e-mail media, the research finding is PHS is more powerful than e-mail to deliver information for physician. From regression analysis, each □ value of PHS is higher than e-mail. The individual using PHS and e-mail is positive to effect the hospital to diffuse of HRR system. Conclusion: The survey of user’s satisfaction of using the HRR system is reached over 70%. However, 60 % of physicians indicates the HRRS provides efficiency and effectiveness each high risk patient’s information causing the information overload. This is the drawback of the implementation HRR system. How to decrease the information overload pressure needs to solve in the near future to improve HRR system. Furthermore, utilization mobile technology to provide two channel communication for physician to access the patient‘s database treatment, test, medication information to integrate all required information to develop the well treatment plan to improve patient safety and reduce patient risk.