[Formulae and special characters can only be approximated here. Please see the pdf version of the abstract for an accurate reproduction.] This thesis concerns the study of homogeneous factorisations of complete graphs with edge-transitive factors. A factorisation of a complete graph Kn is a partition of its edges into disjoint classes. Each class of edges in a factorisation of Kn corresponds to a spanning subgraph called a factor. If all the factors are isomorphic to one another, then a factorisation of Kn is called an isomorphic factorisation. A homogeneous factorisation of a complete graph is an isomorphic factorisation where there exists a group G which permutes the factors transitively, and a normal subgroup M of G such that each factor is M-vertex-transitive. If M also acts edge-transitively on each factor, then a homogeneous factorisation of Kn is called an edge-transitive homogeneous factorisation. The aim of this thesis is to study edge-transitive homogeneous factorisations of Kn. We achieve a nearly complete explicit classification except for the case where G is an affine 2-homogeneous group of the form ZR p x G0, where G0 is less than or equal to ΓL(1,p to the power of R). In this case, we obtain necessary and sufficient arithmetic conditions on certain parameters for such factorisations to exist, and give a generic construction that specifies the homogeneous factorisation completely, given that the conditions on the parameters hold. Moreover, we give two constructions of infinite families of examples where we specify the parameters explicitly. In the second infinite family, the arc-transitive factors are generalisations of certain arc-transitive, self-complementary graphs constructed by Peisert in 2001.