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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Avaliação dos fatores de risco para osteoporose em mulheres na pós-menopausa

Buttros, Davi de Araújo Brito [UNESP] 09 February 2011 (has links) (PDF)
Made available in DSpace on 2014-06-11T19:26:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-02-09Bitstream added on 2014-06-13T20:15:06Z : No. of bitstreams: 1 bruttos_dab_me_botfm.pdf: 462681 bytes, checksum: 038e3f95141da86625e1f48b217bffe6 (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Avaliar o perfil da densidade mineral óssea (DMO) e os fatores de risco associados à osteoporose na pós-menopausa. Realizou-se estudo clínico-transversal com 431 mulheres. Idade entre 40-75 anos, atendidas ambulatorialmente em Hospital Universitário. Incluíram-se mulheres com: amenorréia>12 meses e idade ≥45 anos ou, ooforectomia ≥40 anos, com valores de DMO (coluna lombar e colo de fêmur) pelo DEXA dos últimos 12 meses. Fatores de risco avaliados: idade, idade e tempo de menopausa, tabagismo, atividade física (30min/5x/sem), artrite reumatóide (AR), uso de corticoterapia e de terapia hormonal (TH), fratura prévia, fratura materna de quadril e índice de massa corpórea (IMC=peso/altura2). Valores séricos de cálcio, fosfatase alcalina (FA) e calciúria-24h foram analisados. Empregou-se teste do Qui-quadrado (variáveis categóricas) e método de regressão logística no risco (odds ratio-OR) para osteoporose. A média de idade foi 54,1 ± 6,9 anos, tempo de menopausa 7,5 ± 5,8 anos, IMC 28,2 ± 5,3kg/m2. Encontrou-se: usuárias de TH 35,9%, exercício regular 27,3%, tabagistas 23,8%, menopausa <40anos 18,1%, fratura prévia 11,8%, fratura materna de quadril 10,7%, corticoterapia 4,8%, AR 4,0%. Pelos critérios da OMS, 106 (24,6%) mulheres apresentavam osteoporose (T-escore≤-2,5DP), 188 (43,6%) osteopenia (-1,0/-2,4DP) e 137 (31,8%) eram normais (≥-1,0DP). Detectou-se osteoporose em 12% das mulheres com idade entre 40-49anos, 21,8% 50-59 anos e 45,7% >60 anos (p<0,001). Osteoporose ocorreu em 11,8% com tempo de menopausa <5anos, 29,4% de 6-10anos, e 41% >10anos (p<0,001). Naquelas com menopausa precoce, 80% apresentaram osteopenia/osteoporose (p=0,032) e com IMC<20kg/m2, 50% osteoporóticas (p<0,001). Nenhuma associação foi observada entre DMO e valores de cálcio (p=0,174), FA (p=0,901) e calciúria (p=0,759). O risco de detectar osteoporose aumentou com idade... / To evaluate bone mineral density (BMD) profiles and their risk factors associated with postmenopausal osteoporosis. A cross-sectional clinical study was performed on 431 women aged 40-75 years and cared for at the outpatient clinic of a University Hospital. Women showing the following characteristics were included: amenorrhea >12 months and age ≥ 45 years or, ooforectomy ≥ 40 years with BMD values (lumbar spine and femur neck) by DXA of the last 12 months. Risk factors evaluated: age, age and time of menopause, smoking, physical activity (30min/5x/week), rheumatoid arthritis (RA), use of corticotherapy and hormone therapy (HT), previous fracture, maternal hip fracture and body mass index (BMI=weight/height2). Serum values of calcium, alkaline phosphatase (AP) and 24-h urinary calcium were analyzed. The Chi-square test was used for categorical variables, and the logistic regression method (odds ratio-OR) was utilized for osteoporosis risk. Mean age was 54.1±6.9 years, menopausal period 7.5±5.8 years, BMI 28.2±5.3 kg/m2. The following were found: HT users 35.9%; regular exercise 27.3%; smokers 23.8%; menopause < 40 years 18.1%; low calcium intake (<400mg/day) 55.3%; previous fracture 11.8%; maternal fracture 10.7%, corticotherapy 4.8%, RA 4.0%. According to WHO criteria, 106 (24.6%) women showed osteoporosis (T- score ≤ -2.5 DP), 188 (43.6%) osteopenia (-1.0/-2.4 DP), and 137 (31.8%) were normal (≥ -1.0 DP). Osteoporosis was detected in 12% of the women aged 40-49 years, 21.8% 50-59 years and 45.7% > 60 years (p<0.001). Osteoporosis occurred to 11.8% with a menopause period < 5 years, 29.4% from 6 to 10 years, and 41% > 10 years (p<0.001). Of the women with early menopause, 80% showed osteopenia/osteoporosis (p=0.032), and of those with BMI < 20kg/m2, 50% were osteoporotic (p<0.001). No association was observed between BMD and calcium values (p=0.174), AP (p=0.901)... (Complete abstract click electronic access below)
12

The effect of parathormone on the mineral content of various vertebrates

Rampone, Alfred J. January 1950 (has links)
The effect of parathormone (Lilly) on the total mineral content of bones and muscles (percentage of ash per gram of dry tissue) was used as a measure of hormone activity. Goldfish, frogs, mice, chicks and pigeons were compared. The effect of the parathormone varied with the species. Goldfish showed no response even with massive doses at high temperatures. Frogs, mice and chicks showed a rise in percent bone ash. In chicks an initial rise was followed by a depression. Mice showed the greatest increase in bone ash. Frogs were less responsive than mice but more responsive than chicks. Pigeons showed a distinct softening of the bones. There was no change in muscle ash in any animals except pigeons, which showed a distinct rise. The parathyroid mechanism, whether it acts directly on bones or kidneys, does not seem to operate in aquatic animals. / Science, Faculty of / Zoology, Department of / Graduate
13

A Radioautographic Study or Parathyroid Hormone and Calcitonin Binding in vivo to Various Tissues from Normal and Osteopetrotic Mutant Rodents

Rouleau, M. F. January 1985 (has links)
Note:
14

Regulation of luteinizing hormone secretion in prepubertal heifers

Schillo, Keith Koehler. January 1981 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1981. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 158-178).
15

The release of luteinizing hormone and prolactin by embryonic turkey pituitary cells in vitro

Greene, Peter Howard. January 1981 (has links)
Thesis (M.S.)--University of Wisconsin--Madison, 1981. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 66-70).
16

Regulation of LH and GnRH secretion during prepubertal development in the bull calf

Rodriguez, Rafael Eduardo, 1963- January 1989 (has links)
A series of experiments were conducted to investigate the regulatory mechanisms governing the absence of and the initiation of pulsatile pituitary LH secretion during the infantile and prepubertal periods of development in the bull calf. In the first experiment, patterns of hypothalamic GnRH secretion into hypophyseal portal vessels were measured in sixteen Holstein bull calves at 2, 5, 8 and 12 weeks of age. The results of this study correlated the attainment of an hourly rate of pulsatile GnRH release to the onset of prepubertal LH secretion. In the second experiment, nine Holstein bull calves were infused with exogenous GnRH (200 ng) on an hourly basis from 1 to 6 weeks of age. From this experiment, we were able to demonstrate that an hourly rate of pulsatile GnRH release stimulates the age-associated changes in the hypothalamic-pituitary axis necessary for initiating pituitary LH secretion during the transition from the infantile to prepubertal period of development.
17

Molecular studies of gonadotropin releasing hormone receptors and estrogen receptors in goldfish (Carassius auratus)

馬智謙, Ma, Chi-him, Eddie. January 2000 (has links)
published_or_final_version / Zoology / Master / Master of Philosophy
18

Development of the induced gonadotropin surge mechanism in the prepubertal heifer

Maze, Timothy D. January 2002 (has links)
Thesis (Ph. D.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains viii, 71 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 61-70).
19

The role of ß-catenin in the gonadotrope transcriptional network interactions with SF1 and TCF /

Binder, April Kay. January 2009 (has links) (PDF)
Thesis (Ph. D.)--Washington State University, December 2009. / Title from PDF title page (viewed on Dec. 16, 2009). "School of Molecular Biosciences." Includes bibliographical references.
20

Seasonal cycle of gonadal steroidogenesis and the effects of luteinizing hormone and luteinizing hormone releasing hormone on the in vitro and in vivo steroidal secretions in monopterus albus /

Chʻen, Hui. January 1900 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1989.

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