The Centers for Medicare and Medicaid Services have been working with hospital networks across the United States to improve health care through education and training on clinical best practices and leadership frameworks. Some organizations have failed to reach the high-quality standards of care expected and have adverse patient care outcomes. The purpose of the study was to determine the relationship between leadership actions, funding type, and clinical care outcomes in participating Partners for Patients hospital programs in Iowa. The secondary variable data were provided from a Partnership for Patients contractor, through the Centers for Medicare and Medicaid Services Organizational Assessment Tool. Multiple linear regression analyses were used to determine the relationship between the leadership actions, funding type, and the clinical quality outcomes of catheter-associated urinary tract infections, central line associated bloodstream infections, falls with injury, and venous thromboembolism. The findings demonstrated no statistically significant relationships between leadership actions, such as completing a leadership checklist, incident dashboard, and board involvement in decision making, and the specified clinical care outcomes. There was a statistically significant relationship between leadership actions of completing a root cause analysis for incidents, federal funding type, and the clinical quality outcomes of falls with injury and venous thromboembolism. The results of this study will be shared with Partnership for Patients program leadership to positively impact patient care. The results may be useful as organizations continue to implement best practices to reduce medical errors, save cost, and increase patient safety.