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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Two-year follow-up of Patients with GestationalDiabetes Mellitus in Örebro County : – a retrospective cohort study

Möller, Julia January 2022 (has links)
Introduction: Gestational diabetes mellitus (GDM) is a risk factor for developing type 2diabetes mellitus (T2DM). However, compliance to postpartum follow-up remains low.The new outcome-based International Association of Diabetes and Pregnancy StudyGroups (IADPSG)-criteria have led to a worldwide increase of GDM prevalence. Thepotential impact of the new IADPSG-critera on the frequency of T2DM/prediabetesdiagnosis, during follow-up of prior GDM-women in Örebro County, has not yet beenstudied. Aim: To investigate whether there is a difference in prevalence of prediabetes/T2DM inGDM-women two years postpartum, based on older GDM-criteria vs. the new lower IADPSG2010/WHO 2013-criteria, and to describe compliance to follow-up in primary health care(PHC). Methods: A retrospective cohort study of 108 GDM-women in Örebro County. Data obtainedfrom medical records: cardiometabolic risk factors, compliance data, outcomes withnormoglycemia used as comparison at follow-up. Results: T2DM and prediabetes were non-statistically significant higher in the old criteriagroup[11 (28.9%) vs. 6 (18.2%), p=0.289] and [12 (30.8%) vs. 5 (15.6%), p=0.137],respectively. Compliance to both 1st and 2nd follow-up was seen in 81 (75%) women. 96(88.9%) to first and 88 (81.5%) to second follow-up. An increase in mean BMI was seen frombaseline to PHC (31 vs. 31.7, p=0.014) as well as an increase in alcohol consumption [4(6.6%) vs. 23 (37.7%), p<0.001]. Conclusions: GDM-diagnosis based on IADPSG-criteria did not show any statisticallysignificant difference in the prevalence of T2DM/prediabetes two years postpartum, whencompared to GDM-diagnosis based on old criteria. Moderate compliance to postpartumfollow-up was observed, with an increased number of dropouts. More research is needed inthis area, following implication of IADPSG-criteria.

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