Based on activity competency model (ACM), this study investigated the perceived importance of professional activities and required knowledge/skills/abilities of three levels of information systems (IS) managers from two sectors of industries. Our findings indicate that the importance of IS managerial activities varies significantly for different levels of management, but does not vary significantly for different industries. The results of this study have implications for management development, training, and IS manager career planning. They can also serve as guideline for recruiting the proper IS managers.