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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

Characterization of slow reacting substances from cat paws

Pai, Jin-Keon. January 1982 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1982. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 87-103).

The investigation of peripheral blood cellular immune responses during infection with Mycobacterium tuberculosis /

Veenstra, Hannelore F. U. January 2007 (has links)
Dissertation (PhD)--University of Stellenbosch, 2007. / Bibliography. Also available via the Internet.

The use of granuloma development in rabbits for monitoring responses to tumor vaccines

Bego, David A. January 1976 (has links)
Methods for detection and control of cancer encompass a large area of today's research. Recent use of granulomas as a model for such detection and control may be a promising field, especially for monitoring tumor antigens and immune responses. These granuloma systems are increasingly becoming vehicles in the study of tumor immunology. Although granulomas may be induced naturally by means of foreign bodies i.e. viral, fungal, or bacterial agents, new methods are being established to produce artificial granuloma systems. These systems include chemical or foreign body implantations followed by tumor vaccine challenges.The research presented here involved the use of a golf ball-induced granuloma for the purpose of establishment of a detection system for immune responses. The use of a golf ball-induced granuloma provided a closed system for monitoring cell-mediated and humoral responses to tumor antigens. Immune responses were monitored by means of hematocrits (packed blood cell counts), white blood cell differential counts, and electrophoretic results.Hematocrit results indicated no great immune response to the closed vaccine injected granuloma systems. Observations made on differential white blood cell counts indicated decreasing neutrophil/lymphocyte ratios for cellular immune responses. Electrophoretic results for granuloma fluids indicated decreases in albumin levels concurrent with increases in peak two, and complete loss of peak three following vaccination. Responses to tumor specific antigens in the form of cell-mediated immune responses are indicated by the results presented in this research. Utilization of the golf ball-induced granuloma system provided a means of separating the cell-mediated and humoral immune responses.Tumor specific antigens elicited various immune responses and provide hope for future identification of tumors by this method. Future development and utilization of the golf ball-induced granuloma system may be potential means of monitoring cell-mediated immune responses to tumor malignancies.

The role of the macrophage in the immune response

Pugh, Christopher W. January 1981 (has links)
No description available.

The role of CTL in the natural history of HIV infection

Hansasuta, Pokrath January 2002 (has links)
No description available.

Characterisation of novel genes in the human major histocompatibility complex : the HSP70 & G9a genes

Milner, Caroline M. January 1991 (has links)
No description available.

The synthesis, mode of action and antiparasitic properties of insect immune peptides

Strode, Clare January 2003 (has links)
No description available.

Cloning and characterisation of cytokine and cytokine receptor genes in rainbow trout, Oncorhynchus mykiss

Daniels, Garry D. January 1997 (has links)
Convincing molecular evidence for the existence of both cytokines and their receptors in teleost fish is presented. TGF-β is present in <I>O. mykiss</I> encoding a 112 amino acid mature peptide. An integrin binding site (RGD) and a characteristic tetrabasic cleavage site (RKKR) are present, as is the TGF-β superfamily motif. The mature peptide has 9 conserved cysteine residues (8 of which occur in pairs) as well as two additional conserved TGF-β superfamily residues (Pro<sub>36</sub> and Gly<sub>46</sub>). TGF-β exhibits a wide range tissue distribution including head-kidney macrophages, PBL, brain, gill and spleen tissue, and is encoded by a 2.5Kb mRNA. The trout TGF-β gene is spread over 7 exons, with an additional intron in exon 7 when compared to mammalian and avian models. Isolation of a partial sequence also reveals the presence of TGF-β in a cyprinid species. Phylogenetic analysis suggests trout TGF-β to cluster with mammalian TGF-β1 isoforms, and the avian (TGF-β4) and amphibian (TGF-β5) homologs. Neither TNF-α or TNF receptors were detected in <I>O. mykiss</I> at either the cellular or molecular level. The use of degenerate primers in PCR lead to the isolation of a partial sequence for <I>O. mykiss</I> MHC class I. A full length CXC-R gene of 1.6Kb isolated from <I>O. mykiss</I> displays approximately 65% identity to mammalian CXC-R4 receptors, exhibits the seven-transmembrane domain structure of the G-protein coupled receptors and a tissue-specific distribution. Characteristic superfamily motifs and a putative glycosylation site are present in the sequence. Along with the major features of the adaptive immune response such as the major histocompatibility complex (MHC), T-cell receptor (TCR) and immunoglobulin (Ig), cytokines are now shown to be present at the level of teleost fish.

Studies on B cell development

Martinez, A. G. January 1989 (has links)
No description available.

Activation antigens in the proliferation and differentiation of normal and malignant human leucocytes

Barnett, David January 1991 (has links)
No description available.

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