Immunological correlates of anger conditions were investigated. Participants were 33 females and 36 males, ranging from 25 to 55 years old. Percentages of total T-lymphocytes, suppressor-T, helper-T, and ratio of helper-T to suppressor-T cells were measured. Differences were found between males and females for Anger Control and Anger Expression. For females, total T-cell percentages correlated with State Anger, Angry Temperament, Anger Out, and the combination of State Anger/Angry Reaction. Suppressor-T cell percentages correlated with State Anger, Trait Anger, Angry Temperament, Anger Out, Anger Expression, and the combination of Angry Temperament/Anger In. Helper-T cells correlated with State Anger, Angry Temperament, Angry Reaction, Anger Out, and Anger Control. Mindbody appears to function in a unified fashion.

The present study set out to investigate the biopsychosocial model of illness using variables previously identified as directly impacting illness or as mediating the relationship between other variables and illness. Oral contraceptive use, stress, and negative affect were investigated as predictors of immunological competence, measured by the level of Immunoglobulin G antibodies to Epstein-Barr Virus Viral Capsid Antigen (EBV-VCA IgG).