In this thesis, we design novel implantable antennas for medical implant communication systems and it could operate with the metamaterial which is the artificial electromagnetic (EM) cover layer. The metamaterial based matching layer placed on the surface of the body can improve the performance of the implantable antenna. First, we propose two layers and three layers antenna design. The three layers antenna features high tolerance, high gain, low-profile and miniaturization. The antenna achieves gain −21.7 dBi and efficiency 0.2%. Compared with other literatures of implanted antenna design, the proposed three layers antenna reveals the best gain with similar dimensions. Furthermore, its frequency response is insensitive to the change of the implanted environment. The conception of impedance matching is applied to further improve the gain of the proposed antenna. The matching layers are realized by utilizing the metamaterial and it is placed between the body and the air. In this case, the gain of the three¡Vlayer antenna can be enhanced by 1.23¡V5.2 dB. Furthermore, we propose a size reduction technique to reduce the thickness of the matching layer. The miniature matching layers can increase the gain of the three¡Vlayer antenna by 1.64 dB and 2.63 dB with the dimension of 40¡Ñ40¡Ñ4mm³ and 60¡Ñ60¡Ñ4mm³ respectively. Finally, we propose a co¡Vdesign method of the antenna and metamaterial. The antenna will resonate after placing metamaterial on the surface of the body. So that we can control the antenna whether to transmit power or not by the circuit design in the biomedical device to detect the return loss of the antenna.