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Synthèse et évaluation pharmacologique de composés indoliques et pyridopyraziniques à visée antitumoraleAntoine, Maud Le Baut, Guillaume. Marchand, Pascal January 2005 (has links)
Thèse de doctorat : Pharmacie. Chimie thérapeutique : Nantes : 2005. / Bibliogr.
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Novel syntheses of indoles, quinoxalines, 2-quinoxalinones, 2-alkylbenzimidazoles and other heterocyclesWallace, Jeffery M. January 1900 (has links)
Thesis (Ph. D.)--West Virginia University, 2003. / Title from document title page. Document formatted into pages; contains xii, 218 p. : ill. Includes abstract. Includes bibliographical references (p. 118-123).
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A study of stereo-electronic factors in the addition of dimethyl acetylene dicarboxylate to substituted 1H- and 3H-indoles /Wai, Sui-man, John. January 1984 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1984. / Caption title.
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Studies on diazoketone rearrangements and application toward the synthesis of welwistatinLam, Shuk-mei, 林淑媚 January 2013 (has links)
published_or_final_version / Chemistry / Doctoral / Doctor of Philosophy
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A study of stereo-electronic factors in the addition of dimethyl acetylene dicarboxylate to substituted 1H- and 3H-indoles衛小文, Wai, Sui-man, John. January 1984 (has links)
published_or_final_version / Chemistry / Master / Master of Philosophy
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The role of indole in plasmid replication in E.coliDuboff, James Steven January 2013 (has links)
No description available.
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Synthetic and mechanistic studies in free radical..Callaghan, Owen January 1999 (has links)
No description available.
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Synthesis and reactivity of some activated heterocyclic compoundsAlamgir, Mahiuddin, Chemistry, Faculty of Science, UNSW January 2007 (has links)
An alternate approach to the synthesis of calix[3]indoles has been demonstrated, but further attempted synthetic approaches to calixindoles using new leaving groups led to uncharacterized polymeric products. The synthesis of new 7,7'-diindolylmethane- 2,2'-dicarbaldehydes gives potential for further ligand design and metal complex formation. In addition, 4,6-dimethoxyindole-7- carbaldehydes have been effectively converted to a range of 6-methoxyindole-4,7-diones by Dakin oxidation. Various electrophilic substitution reactions have been performed on the 4,6-dimethoxybenzimidazoles. Formylation, acylation, acid catalyzed addition of formaldehyde and nitration revealed that the activated benzimidazoles are less reactive at the specified C-7 position compared to the analogous indoles. The key starting material for a potential calixbenzimidazole was synthesized by the selenium dioxide oxidation of 2-methyl-7-formyl-4,6-dimethoxybenzimidazole and by oxidative cleavage of 4,6-dimethoxy- 2-styrylbenzimidazole by Lemieux-Johnson reagent followed by reduction. Nevertheless, attempted preparation of calixbenzimidazole from 2-hydroxymethyl-4,6-dimethoxy benzimidazole led to formation of a dibenzimidazolyl ether. The synthesis of some novel activated bisbenzimidazoles has been developed. Furthermore, benzimidazoles were incorporated into new ligand systems which have led to a wide range of acyclic quadridentate neutral metal complexes. Activated benzimidazoles overall illustrate one electron irreversible oxidation to form a radical cation followed by multielectron oxidations. On the other hand, the nickelII and cobaltII benzimidazole metal complexes investigated showed one electron ligand centered reversible reduction. Irreversible radical cation oxidation followed by multielectron oxidation of the metal complexes further demonstrates the rich electrochemical nature of the 4,6-dimethoxybenzimidazoles. Some novel 7-(indol-2-yl)-4,6-dimethoxybenzimidazoles were prepared with indolin-2-one and triflic anhydride and an alternate procedure afforded 2-(4,6-dimethoxyindol-7-yl)-benzimidazoles from activated indoles and 2-benzimidazolinone. Two new isomeric series of 2-substituted-5,7-dimethoxybenzothiazoles and 2-substituted-4,6-dimethoxybenzothiazoles were synthesized via Jacobson cyclization. The two strategically placed electron donating methoxy groups activate these benzothiazoles to undergo various electrophilic substitutions at the 4- and 7- positions respectively.
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Equilibria in hydrogenation of esters and indolesBurks, Robert E. January 1947 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1947. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 78-79).
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Study of Diels-Alder reactions in the syntheses of Yuehchukene analogues and optically active Yuehchukene /Cao, Guo-an. January 1993 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1993.
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