Wire Electrical Discharge Machining (WEDM) is a nontraditional machining process used for machining intricate shapes in high strength and temperature resistive (HSTR) materials. WEDM provides high accuracy, repeatability, and a better surface finish; however the tradeoff is a very slow machining rate. Due to the slow machining rate in WEDM, machining tasks take many hours depending on the complexity of the job. Because of this, users of WEDM try to predict machining rate beforehand so that input parameter values can be pre-programmed to achieve automated machining. However, partial success with traditional methodologies such as thermal modeling, artificial neural networks, mathematical, statistical, and empirical models left this problem still open for further research and exploration of alternative methods. Also, earlier efforts in applying the decision tree rule induction algorithms for predicting the machining rate in WEDM had limitations such as use of coarse grained method of discretizing the target and exploration of only C4.5 as the learning algorithm. The goal of this dissertation was to address the limitations reported in literature in using decision tree rule induction algorithms for WEDM. In this study, the three decision tree inductive algorithms C5.0, CART and CHAID have been applied for predicting material removal rate when the target was discretized into varied number of classes (two, three, four, and five classes) by three discretization methods. There were a total of 36 distinct combinations when learning algorithms, discretization methods, and number of classes in the target are combined. All of these 36 models have been developed and evaluated based on the prediction accuracy. From this research, a total of 21 models found to be suitable for WEDM that have prediction accuracy ranging from 71.43% through 100%. The models indentified in the current study not only achieved better prediction accuracy compared to previous studies, but also allows the users to have much better control over WEDM than what was previously possible. Application of inductive learning and development of suitable predictive models for WEDM by incorporating varied number of classes in the target, different learning algorithms, and different discretization methods have been the major contribution of this research.