Following the approach of knowledge generation of economy, knowledge has become a mean of business survival competition and an advantageous implement or creative competition. How to share knowledge among businesses as to expand the productivity and ability, as to produce new knowledge and promote competitive advantages out of mutual agitation of knowledge, and how a business can applicably perform the informative facilities as to circulates in this scientific generation, shall be the one and only way of continuous operation of present business. Firstly, the research shall establish a relevant theory of knowledge management, develop and design questionnaires in connection with the local¡¦s transnational business trading. The relationship between the movement of multi-national business knowledge management and global configuration strategies can be conferred with the researched statistical analysis. Then, the research shall discuss the system that the business shall operate as to push the knowledge management and the influences that may incur. Secondly, the research shall discuss the relevance of business qualities and knowledge management, as to clarify the influences of knowledge transferable strategy under different industrial stages. Lastly, the research will describe the relationship between the subject of knowledge management and global resources configurative strategies. The research came up with the following discoveries after applying quantitative analysis and collected data integration: 1. The greater tends of organizational culture toward open-up and active shape, the greater help it will be for the business movement for knowledge management. In addition, basic information development of knowledge organization has influences toward the organizational movement of creating new knowledge, transfer of knowledge and management of knowledge. In other words, the more complete that the business information construction is, the more systemized and greater help it will be to push the knowledge management. 2. An enterprise must pay great attention to the transfer of knowledge during its development period. During the business development period, the entire environment is developing and changing rapidly. Thus, the enterprise must have great alert of the market behavior, and mostly important, to have frequent communication with the employees and share experiences with them. 3. There are greater influences on the distribution of organizational resources during the development period of the business¡¦s industrial stage rather than its maturity period.