Thesis (Ph.D.)--Aberdeen University, 2008. / Title from web page (viewed on Feb. 24, 2009). Includes bibliographical references.

Thesis (Ph. D.)--University of Adelaide, 1984. / Appendix 7, (3 leaves) in pocket. Includes bibliographical references.

Thesis (M. Env. St.)--University of Adelaide, 1984. / Dated 1983. Includes bibliographical references (leaves 174-181).

Within the European Union, the Registration, Evaluation, Authorisation and restriction of Chemicals (REACH) Regulation 2006, requires the registration of chemicals by manufacturers and suppliers by a number of deadlines from 2008- 2018. Registrants must prepare a dossier of substance information, incorporating a chemical safety report and exposure assessment for the work activities for which the substance is used. Several computer-based screening (Tier 1) tools mentioned in the REACH guidance are used by Registrants to assess exposure: the ECETOC Targeted Risk Assessment (TRA); STOFFENMANAGER®; the EMKG-EXPO-TOOL and MEASE. As screening tools, they are expected to generate overestimates of exposure, thus allowing identification of situations of concern requiring more detailed assessment. The study aimed to carry out a comprehensive evaluation of the tools' validity, by comparison of their predictions with workplace measurements of inhalation exposure and their reliability, through assessment of consistency of operation by different users. Comparison of tool predictions of exposure with measurement data (n=3941) from a wide range of European and North American sources suggested that the tools generated overestimates in the majority of cases, with exceptions noted in certain process types and substance forms. Extremely large variability was observed in tool outputs generated by a group of representative users (n=146) when assessing identical exposure situations. A small number of input parameters drove most of the variation; the task descriptor, risk management measures and type of setting. Further calibration and review of the tool predictions are required to ensure that they generate consistent overestimates of exposure. Systems should be implemented to reduce between-user variability, for example user certification; round-robin exercises and team-based assessments. The study findings will assist in increasing the consistency of use and validity of the tools, thus increasing the overall levels of worker health protection and minimising unnecessary business risk management expenditure on redundant exposure controls.

Thesis (D.Psych.)--Murdoch University, 2009. / Thesis submitted to the Faculty of Health Sciences. Includes bibliographical references.

Research was initiated to examine the feasibility of removing the majority of 4-PCH from the XSBR latex employed in carpet manufacturing. The reduction of 4-PCH from such latices would lend insight into the control of certain carpet related illnesses.

Chemical exposure of the skin has become a route of entry of some chemicals into the body and has come under major review in recent times. This research aims to develop a method of estimating skin exposure that is both reliable and non-prohibitive in cost. This involved the design and testing of skin patches adaptable for monitoring skin exposure to chemicals using several different types of absorbents which could be easily worn against skin. The final design of the patch used either activated charcoal or tenax as the absorbing medium. The patches were then desorbed with a solvent in order to analyse the chemicals. The results of the study showed that many skin exposures do not have a direct relationship with inhalation exposures, which is important because currently there are no estimates of the levels of skin exposures that may have potential long term health effects. The patch has proved successful for detecting the presence and determining the amount of chemicals that come in contact with the skin. Charcoal patches have the widest application, but are not suitable for all situations and tenax should be used on these occasions. / Doctor of Philosophy (PhD)

Dated 1983. Bibliography: leaves 174-181.

Appendix 7, (3 leaves) in pocket. Includes bibliography.

Appendix 7, (3 leaves) in pocket / Includes bibliography / 1 v. (various foliations) : ill ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 1984