Even though most clinical information systems (CIS) today are technically sound, the number of successful implementations of these systems is low. For that reason, understanding the characteristics and challenges for organizations implementing CIS is now considered key to successful information technology deployment (Lorenzi & Riley, 1997). Although theory driven information systems models and CIS studies exist, an integrated model to predict a successful CIS has not been evaluated. The purpose of this research was to evaluate the ability of a theoretically-based integrated model of CIS success (CISSM) to predict a successful CIS from the clinicians' perspective. Data were collected and analyzed from 234 registered nurses in 4 hospitals who had used the Cerner PowerChart Admission Health Profile (AHP) longer than 3 months. Construct validity and internal consistency reliability of the 23-item online instrument were established. The results of stepwise multiple regression analyses provided tentative support for the CISSM model.

This thesis aimed to investigate the determinants of system satisfaction and the intention to systematically integrate a system from a continuous use perspective, where system use is mandatory. For this purpose, two identical questionnaires were distributed to collect data, 15 months apart. Respondents taking part in this study are healthcare multi-professionals who pertain to a work-group at an intensive care unit, at a large Swedish hospital. To evaluate the questionnaire data a research model was conceptualized, grounded in prior information system continuance research. It is also significantly influenced by the UMISC metamodel, conceptualized and suggested by Hadji & Degoulet (2016). The collected data was then analyzed using a two-stage analysis where one aspect was comparative, i.e., a comparison of the data between the two questionnaires, and the other was explorative, wherein research model constructs and their relations were evaluated. This analysis provided significant insight into the determinants of system satisfaction. However, regarding the determinants of the intention to systematically integrate as well as the research model itself, neither could be validated in this study. Nevertheless, these results allowed for a modified model to be conceptualized, with potentially promising results.