Hypothesis: That infrainguinal arterial bypass procedures are associated with an ischaemia-reperfusion injury and that this may be reduced by administration of sodium nitroprusside, a nitric oxide donor. First study: 28 subjects, with critical limb ischaemia, undergoing infrainguinal bypass were randomised to receive sodium nitroprusside (0.1 μg/kg body weight/min) (n=15) or placebo (n = 13), infused into the operated limb, during the performance of the second or distal anastomosis and the infusion continued for twenty minutes after. Blood sampling and a doppler studies were performed. 9 patients undergoing varicose vein operations were also examined. The results indicated that application of the proximal clamp resulted in ischaemia and reperfusion with associated neutrophil activation. Sodium nitroprusside resulted in vasodilatation but had no effect on either parameter. Bypass patients had higher baseline neutrophil activation than the varicose vein group. Second Study: 30 further bypass patients ere randomised (treatment n = 15, placebo n = 15) with the infusion commencing at the time of the proximal anastomosis. Blood and urine sampling and doppler studies were performed. Changes in plasma antioxidant status, microalbuminuria and enzymuria occurred only in the placebo group indicating that, in addition to vasodilating the critically ischaemic limb, the nitric oxide donor may have been protective. Paradoxically, myeloperoxidase levels rose only in the treatment group but there was no evidence of increased free radical activity or permeability changes associated with this. Conclusion: Infrainguinal bypass is associated with an ischaemia-reperfusion injury which begins at the time of first clamp application. These procedures also result in a small but significant decrease in antioxidants and an increase in permeability. Sodium nitroprusside, a nitric oxide donor, administered into the operated limb appears to be protective against these changes and is an effective peripheral vasodilator.

No description available.

No description available.

I Sverige drabbas varje år mer än 150 barn av allvarliga skador under infusionsbehandling. I nära samarbete med Hallands sjukhus Halmstad och har ett varningssystem utvecklats för att detektera infiltration under infusionsbehandling. Detta är en produkt som efterfrågats i 30 år av barnläkaren och idéskaparen till projektet, Kent-Åke Henricson. Infiltration är en medicinsk term som beskriver när infusionsvätska läcker ut i omgivande vävnad runt blodvenen. Beroende på vilket läkemedel som infiltrerats kan skadans allvarlighetsgrad variera från en lätt hudreaktion till allvarlig nekros. Vid en allvarlig infiltration förlängs vårdtiden vilket blir kostsamt för sjukhusen. Moneo underlättar arbetet för sjukvårdspersonal likaså ger det barn en trygg och säker behandling. Idag görs rutinkontroller av sjuksköterska upp till varannan timme på droppets insticksställe, vilket är både tidskrävande och störande för patienten. Produkten fungerar som ett kompletterande stöd vid behandling och är anpassad för att användas med befintlig infusionsutrustning. Barn är aktiva patienter och produkten är utformad för att tillåta fysiska rörelser och genom sin lätta vikt och smarta konstruktion är produkten bekväm för patienten och enkel att integrera i sjukvårdspersonalens rutiner. Projektgruppen är stolt och nöjd över att presentera sitt examensarbete Moneo, som resulterat i en produkt som ger säkrare vård och förhindrar onödigt lidande för barn. Ingen patient ska behöva skadas i vården, det är en grundprincip för all vårdverksamhet. / Each year more than 150 children suffer from severe injuries during IV infusion therapy in Sweden. In close cooperation with Hallands sjukhus Halmstad, a new warning system has been developed for detection of infiltration during IV infusion. For more than 30 years this kind of product has been requested from pediatrician and innovator Kent- Åke Henricson. Infiltration is a medical term used to describe when you infuse medical drugs into the surrounding tissue instead of into the vein. Depending on the type of medicine that has been infiltrated, the severity of the injury varies from light skin reaction to severe necrosis. A severe infiltration leads to extended hospital stays for the patient, which can be costly for the hospital. Today a nurse does regular checkups every two hours at the puncture site in order to insure that the medicine is being delivered properly. This is very time consuming for medical staff, as well as, annoying for the patient. Our product will function as an additional safe guard during infusion therapy and is adapted to be used with existing infusion devices. Moneo allows for easier monitoring by medical staff while giving children a more safe treatment. Children are active patients and Moneo’s light weight and smart design allows for physical movement and comfort of the patient. It is also easily integrated into the existing procedures and routines of the medical professionals. The project group is proud and happy to present their final thesis, Moneo, which has resulted in a product that can eliminate unnecessary suffering in the children receiving IV infusion therapy thereby providing a more safe treatment option. It is a basic medical principle that no patient should suffer negative side effects of a medical procedure. Moneo can be used to avoid these kinds of concerns.

Zugl.: Giessen, Universiẗat, Diss., 2007.

Universiẗat, Diss., 2007--Giessen.

Freie Universiẗat, Diss., 2005--Berlin. / Dateiformat: zip, Dateien im PDF-Format. Erscheinungsjahr an der Haupttitelstelle: 2005.

abstract: The use of educational technologies as a tool to improve academic achievement continues to increase as more technologies becomes available to students. However, teachers are entering the classroom not fully prepared to integrate technology into their daily classroom teaching because they have not been adequately prepared to do so. Teacher preparation programs are falling short in this area because educational technology and the role of technology in the classroom is seen as an extra component to daily teaching rather than a central one. Many teacher preparation programs consist of one stand-alone educational technology course that is expected to prepare teachers to integrate technology in their future classrooms. Throughout the remainder of the program, the teachers are not seeing educational technologies modeled in their other core courses, nor are they getting the hands-on interaction necessary to become more confident in using these technologies with their future students. The purpose of this study was to examine teachers' views of educational technology in the classroom from those enrolled in a graduate program. The study consisted 74 first- and second-year teachers who were enrolled an alternative teacher preparation program. Thirty-four of the teachers received the Integrating Curriculum and Technology (iCAT) intervention and the remaining 40 teachers were part of the control group. Each teacher completed a pre- and post-intervention questionnaire and 23 of the 74 teachers participated in one of three focus group interviews. Additional data from the teachers' course instructors were gathered and analyzed to compliment the focus group and quantitative data. Results showed that iCAT participants' scores for confidence in using technology and efficacy for using educational technology increased at a faster rate than the control group participants' scores. Similarly, confidence in using technology, perceptions about integrating technology in the classroom, and efficacy for using educational technology could be predicted by the amount of hands-on interaction with technology that the teachers received during their graduate course. The discussion focuses on recommendations for infusing technology throughout teacher preparation programs so that teachers have the tools to prepare their students to use a variety of technologies so that their students can be better prepared to complete in today's workforce. / Dissertation/Thesis / Ph.D. Educational Technology 2012

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The researches about service encounters often aimed at the interaction between customers and employees before. With the development of technology, it has been introduced into service industry to assist with service providing. Not only did technology change the original relation of interpersonal contact, but also it replied the interaction between customers and employees. Therefore, this study explored the change of entire satisfaction sources after the technology infusion in service encounters from the customer¡¦s point of view. There were two stages in this study. The first stage was an exploratory research and sampled from the customers in the largest chain of hair beauty in Kouhsiung. Using critical incidence technique to collect and analyze the data, we found the entire satisfaction/dissatisfaction sources and compared the difference between technology infusion or not. The second stage was a conclusive research and sampled from the female students in the dormitory in National Sun Yet-san University. The findings from the first stage were proved by experimental design and ANOVA. There were five findings in this study. 1. The satisfaction/dissatisfaction factors were categoried to five sources. They were reliability (core servie, service performance resulting from technology infusion, and comprehensive performance), responsiveness (flexible service precess and dealing with the special conditions), Assurance (good communication and professional performance or courtesy of non-core service), Empathy (service manners and customerized service), and tangibles (environment and atmosphere, technology and equipments). 2. Technology infusion in service encounters could increase entire customer satisfaction and decrease entire customer dissatisfaction. 3. Besides technology itself could directly influence the customer satisfaction, the company could elevate the level of customer satisfacton by indirectly improving the interpersonal interatction in service encounters. 4. The perceived reliability influenced the intention of using new technology, the company image of improving continuously and the morden image. Assurance influenced the intention of using new technology, the company image of concerning about customer and recommendation intention. 5. The higher the assurance was, the higher satisfaction of technology infusion in service encounters could be.