Spelling suggestions: "subject:"insecticides -- aphysiological effect"" "subject:"insecticides -- atphysiological effect""
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Specificity of binding of 36Cl-dieldrin to various proteinsJakubowski, Thomas, 1948- January 1972 (has links)
No description available.
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The determination of parathion and possible metabolites in the milk, blood and urine of dairy cows after experimental feeding of parathionPankaskie, Joseph Edward. January 1951 (has links)
Call number: LD2668 .T4 1951 P3 / Master of Science
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Partition of DDT among intracellular organellesVessey, Donald A. January 1967 (has links)
No description available.
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Effects of three malathion treatments on fecundity, longevity and weight of the house fly, Musca domestica L.Ouye, Milton Tamotsu. January 1957 (has links)
Call number: LD2668 .T4 1957 O95 / Master of Science
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Hemoglobin adducts of the organophosphate insecticide azinphos-methylBailey, Bonnie J. 05 May 2000 (has links)
Reported here is an investigation to determine if azinphos-methyl (AZM), an
organophosphate insecticide, adducts to hemoglobin, and if so, whether the
hemoglobin adduct could be used as a quantitative marker of occupational AZM
exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin
in erythrocytes forming an adducted protein. We administered radiolabled AZM to
rats and found a stable, dose-dependent association of radioactivity with hemoglobin.
The decline in hemoglobin-associated radioactivity followed the expected kinetics of
erythrocyte turnover in rats. We examined hemoglobin isolated from these rats by
high-pressure liquid chromatography, liquid scintillation counting, and electrospray
ionization mass spectrometry. These analyses provided evidence of AZM or an AZM
metabolite binding to one of the beta proteins of hemoglobin. In vitro incubation of
AZM with hemoglobin in a liver microsome system indicated an AZM adduct to
heme. Further research is necessary to fully characterize the adduct and determine
whether this biomarker will be useful for monitoring human exposure to AZM. / Graduation date: 2000
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Physical and insecticidal stress effects on the foregut of the cockroaches Leucophaea maderae (Fabr.) and Periplaneta americana (L.)Ameel, John Jules. January 1965 (has links)
Call number: LD2668 .T4 1965 A51 / Master of Science
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Die rol van dieldrin in waterbesoedeling met spesiale verwysing na die invloed daarvan op varswaterfaunaVan Jaarsveld, Jan Harm 11 February 2014 (has links)
D.Sc. / Please refer to full text to view abstract
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Effects of biogenic amines and formamidine insecticides on the central production of flight by Manduca sextaClaassen, Dale E. January 1985 (has links)
Call number: LD2668 .T4 1985 C52 / Master of Science
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FACTORS INFLUENCING ARIZONA BAT POPULATION LEVELSReidinger, Russell Frederick, 1945- January 1972 (has links)
No description available.
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Behavioral Outcomes and Molecular Marker Modulation during Learning and Memory Formation following Developmental Exposure to Organophoshorus InsecticidesJohnson, Frank Orlando 15 December 2007 (has links)
Effects of developmental exposure to chlorpyrifos (CPS) or methyl parathion (MPS) on visuospatial, adaptive fear response, and passive avoidance memory and the signaling mechanisms responsible for these neurocognitive changes were investigated. Using an incremental low dose regimen, rat pups were orally gavaged daily with either corn oil (vehicle), CPS, or MPS from postnatal day 1 (PND1) -PND21. Cholinesterase activity was significantly inhibited with the highest dosages of CPS and MPS for up to 19 days after the last dosages. OP exposure impaired working and reference memory in males whereas in the females, enhancement occurred following CPS exposure. In addition, the adaptive fear response and passive avoidance retention memory was impaired in males whereas differential changes occurred in females. Accordingly, the behavioral deficits observed in males were persistent whereas the enhancement in females was transient. Males were more sensitive to OPs than females in that the medium and high dosages of CPS and MPS produced greater effects in females whereas all dosages of both compounds produced effects in males. Training in the radial arm maze significantly increased protein kinase C gamma (PKC ) expression and activity in the hippocampal membrane fraction of control rats whereas exposure to OPs exhibited a significant decrease in PKC and PKC immunoreactivity in both untrained and trained rats. However, MPS exposed females exhibited a significant increase in PKC expression in the cytosolic fraction but this was not related to improved memory. Reduction of membrane PKC expression and activity and cytosolic PKC expression and activity seemed to be related to visuospatial learning and memory deficits in exposed males but not exposed females. Brain-derived neurotrophic factor (BDNF) gene expression in the hippocampus was significantly increased (60%) in trained control males as compared to untrained control males. In contrast, trained and untrained females exhibited similar levels of BDNF gene expression. However, exposure of both sexes to either CPS or MPS significantly reduced the expression of BDNF in trained rats. In summary, these data indicate that OP exposure induced gender-specific changes in working memory formation and altered PKC isozyme levels/activity and BDNF expression.
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