As refresher courses are getting popular in Taiwan, it is good news for those who want to continue their studies at the same time of working. However, an individual social role will be getting more complicated during this situation of inter-role conflicts. While a full-time worker also needs to act as a student after work, will he encounter the inter-role conflicts of learning and working? This study aims on students who are taking refresher courses at public or private two-year junior college, two-year college, and university in Kaohsiung. We try to discuss the relationship between inter-role conflicts, social support and learning burnout of students who are taking refresher courses. We indicate the relationship between inter-role conflicts, social support and learning burnout due to different background characteristics of respondents. The study result is supported by empirical data and provides some suggestions for those who want to take refresher courses and further researchers. We send out 800 questionnaires and get 602 returned ones. The final valid questionnaires are 589 and the return rate is 76.62%. The result is indicated as below: 1. Most of respondents in this study are female, single, and study in national two-year junior college right now. Their tenure in current company is 1-5 years. Most of them have strong motivation of self actualization even they all play different social roles now. The age of most respondents is between 31-40 and most of them work in manufacturing industries and would prefer to study at school in short distance. 2. The result indicates the inter-role conflicts that learning interferes working or learning and working interfere each other have strong impact on learning attitude. Besides, the inter-role conflicts that learning interferes working or learning and working interfere each other have strong impact on interpersonal relationship alienation. The three kinds of inter-role conflicts all have strong impact on low learning emotion. Furthermore, the inter-role conflicts which learning and working interfere each other have strong impact on emotion burnout. 3. The moderation effects of families¡¦ support, managers¡¦ support, colleagues¡¦ support and classmates¡¦ support are partially supported in this study.